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ID 117254
Author
Keywords
Multiple myeloma (Plasma cell myeloma)
Bone diseases
Osteoclasts
Osteoblasts
Osteocytes
Content Type
Journal Article
Description
Multiple myeloma (Plasma cell myeloma), a malignancy of the plasma cells, exhibits tumor expansion preferentially in the bone marrow and the development of bone-destructive lesions. Multiple myeloma is still an incurable disease with changes in the bone marrow microenvironment in favor of the survival and proliferation of multiple myeloma cells and bone destruction. In this review, we described the recent findings on the regulators involved in the development of myeloma bone diseases, and succinctly summarize currently available therapeutic options and the development of novel bone modifying agents for myeloma treatment.
Journal Title
Japanese Dental Science Review
ISSN
18827616
NCID
AA12334461
Publisher
Japanese Association for Dental Science|Elsevier
Volume
57
Start Page
164
End Page
173
Published Date
2021-09-23
Rights
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Oral Sciences
University Hospital
Medical Sciences