Total for the last 12 months
number of access : ?
number of downloads : ?
ID 117356
Author
Furukawa, Satoshi Japan Aerospace Exploration Agency
Chatani, Masahiro Showa University
Higashitani, Atsushi Tohoku University
Higashibata, Akira Japan Aerospace Exploration Agency
Kawano, Fuminori Matsumoto University
Numaga-Tomita, Takuro Shinshu University
Ogura, Toshihiko Tohoku University
Sato, Fuminori Kyoto University
Sehara-Fujisawa, Atsuko Kyoto University
Shinohara, Masahiro National Rehabilitation Center for Persons with Disabilities
Shimazu, Toru Japan Space Forum
Takahashi, Satoru University of Tsukuba
Watanabe-Takano, Haruko National Cerebral and Cardiovascular Center
Content Type
Journal Article
Description
The musculoskeletal system provides the body with correct posture, support, stability, and mobility. It is composed of the bones, muscles, cartilage, tendons, ligaments, joints, and other connective tissues. Without effective countermeasures, prolonged spaceflight under microgravity results in marked muscle and bone atrophy. The molecular and physiological mechanisms of this atrophy under unloaded conditions are gradually being revealed through spaceflight experiments conducted by the Japan Aerospace Exploration Agency using a variety of model organisms, including both aquatic and terrestrial animals, and terrestrial experiments conducted under the Living in Space project of the Japan Ministry of Education, Culture, Sports, Science, and Technology. Increasing our knowledge in this field will lead not only to an understanding of how to prevent muscle and bone atrophy in humans undergoing long-term space voyages but also to an understanding of countermeasures against age-related locomotive syndrome in the elderly.
Journal Title
npj Microgravity
ISSN
23738065
Publisher
Arizona State University|NASA|Springer Nature
Volume
7
Start Page
18
Published Date
2021-05-26
Rights
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences