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ID 117447
Title Alternative
Hybrid Brachytherapy of Cervical Cancer
Author
Itami, Jun Shin-Matsudo Central General Hospital|National Cancer Center Hospital
Murakami, Naoya National Cancer Center Hospital
Watanabe, Miho Chiba University
Sekii, Shuhei Hyogo Prefectural Cancer Center
Kasamatsu, Takahiro Tokyo Metropolitan Bokuto Hospital
Kato, Shingo Saitama Medical University
Hirowatari, Hisako Tokyo Rinkai Hospital
Ando, Ken Gunma Cancer Center
Ohno, Tatsuya Gunma University
Okamoto, Hiroyuki National Cancer Center Hospital
Okuma, Kae National Cancer Center Hospital
Igaki, Hiroshi National Cancer Center Hospital
Keywords
cervical cancer
interstitial
intracavitary
brachytherapy
three-dimensional image-guided
Content Type
Journal Article
Description
High-dose-rate brachytherapy by remote afterloading is now performed under three-dimensional image guidance by CT or MRI. Three-dimensional image-guided brachytherapy in cervical cancer disclosed that the traditional intracavitary brachytherapy by Manchester method cannot deliver an adequate dose to the large tumor with resulting local recurrence. To improve the local control rate, combined interstitial and intracavitary (hybrid) brachytherapy can increase the dose to the large parametrial involvement without increasing the dose to the rectum and bladder. Whether hybrid brachytherapy can be performed safely on a multi-institutional basis remains to be studied. From 2015, phase I/II study of hybrid brachytherapy was launched in Japan, and it was revealed that hybrid brachytherapy can be performed safely and with a high quality of radiation dose distribution in a multi-institutional study. In Japan, the number of patients undergoing hybrid brachytherapy in cervical cancer is rapidly rising. Education and clinical trial are very important to establish hybrid brachytherapy in the management of cervical cancer.
Journal Title
Frontiers in Oncology
ISSN
2234943X
Publisher
Frontiers Media S.A.
Volume
11
Start Page
809825
Published Date
2022-01-13
Rights
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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language
eng
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departments
Medical Sciences