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ID 117798
Title Alternative
BACTERIAL ADAPTATION TO QAC
Author
Maeda, Takuya The University of Tokushima
Keywords
Quaternary ammonium compound
Bis-QAC
Bacterial adaptation
Resistance to disinfectant
Cell surface hydrophobicity
Content Type
Journal Article
Description
The adaptation of bacteria to mono-and bis-type quaternary ammonium compounds (QACs) was carried out and studied. The minimum inhibitory concentration (MIC) of bis-QACs against the bacteria in contact with bis-QACs was nearly the same as that against the control. However, the MIC of mono-QAC against the strains adapted to mono-QAC was higher than that against the control. Moreover, bis-QACs were effective against even the strains adapted to mono-QAC. As the cell surface of the strains adapted to mono-QAC changed to hydrophilic, the difference in the bacterial adaptation was thought to arise from a potent property of bis-QACs whose antimicrobial characteristics are independent of the change in the cell surface hydrophobicity.
Journal Title
Biocontrol Science
ISSN
13424815
18840205
NCID
AA11169621
Publisher
The Society for Antibacterial and Antifungal Agents, Japan
Volume
8
Issue
1
Start Page
37
End Page
42
Published Date
2003-03-20
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Bioscience and Bioindustry