Critical Limb Threatening Ischemia Due to Severe Polyarteritis Nodosa : A Case Report

Yagi, Issei; Yagi, Shusuke; Nakanishi, Keisuke; Tezuka, Kazuki; Matsuyama, Kazuo; Aibara, Yasushi; Ishida, Takuya; Yoneda, Hiroto; Yamamoto, Masaki; Ise, Takayuki; Yamaguchi, Koji; Yamada, Hirotsugu; Soeki, Takeshi; Wakatsuki, Tetsuzo; Kitagawa, Tetsuya; Nishioka, Yasuhiko; Sata, Masataka

doi:10.2169/internalmedicine.4149-24

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Use this link to cite this item : https://repo.lib.tokushima-u.ac.jp/119631

ID	119631
Author	Yagi, Issei Tokushima University Yagi, Shusuke Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Nakanishi, Keisuke Tokushima University Tezuka, Kazuki Tokushima University Matsuyama, Kazuo Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Aibara, Yasushi Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Ishida, Takuya Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Yoneda, Hiroto Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Yamamoto, Masaki Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Ise, Takayuki Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Yamaguchi, Koji Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Yamada, Hirotsugu Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Soeki, Takeshi Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Wakatsuki, Tetsuzo Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Kitagawa, Tetsuya Shikoku Central Hospital of the Mutual aid Association of Public, School Teachers Tokushima University Educator and Researcher Directory KAKEN Search Researchers Nishioka, Yasuhiko Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Sata, Masataka Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords	Vasculitis Digital gangrene Mononeuropathy multiplex Polyarteritis nodosa
Content Type	Journal Article
Description	A delayed diagnosis of polyarteritis nodosa may lead to critical limb-threatening ischemia (CLTI). A 74-year-old woman presented with left-foot pain and was treated with oral vasodilators and antiplatelet agents. However, the distal ischemia progressed to CLTI, including gangrene of the fingers and toes, and bilateral foot dropping appeared because of peroneal nerve paralysis. Angiography of the extremities revealed obstruction and stenosis of medium-sized arteries. Based on the progressive distal gangrene, mononeuropathy multiplex, and pathological findings of necrotic vasculitis, polyarteritis nodosa was diagnosed, and the patient's condition improved. A biopsy and neurological examination are essential for the appropriate diagnosis of PAN and immediate treatment.
Journal Title	Internal Medicine
ISSN	13497235
Publisher	The Japanese Society of Internal Medicine
Published Date	2024
Rights	The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID	414760
DOI (Published Version)	10.2169/internalmedicine.4149-24
URL ( Publisher's Version )	https://doi.org/10.2169/internalmedicine.4149-24
FullText File	internalmedicine.pdf 1.07 MB
language	eng
TextVersion	Publisher
departments	Medical Sciences University Hospital