ID 109862
Title Transcription
エンショウ カンキョウ ニヨル シズイ サイボウ ノ カンサイボウカ : シズイ サイボウ ブンカ ニ アタエル シュヨウ エシ インシ TNF-α ノ エイキョウ
Title Alternative
Reprogramming of Human Dental Pulp Cells Mediated by Inflammatory Signals : Effects of TNF-α on Human Dental Pulp Cell Differentiation
Author
Ueda, Mayu Department of Stomatognathic Function and Occlusal Reconstruction, Tokushima University Graduate School, Institute of Biomedical Sciences Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
歯髄細胞
TNF-α
幹細胞化
Content Type
Journal Article
Description
During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factoralpha (TNF-α) or interleukins, act in the initial 48 hours (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells but also in inducing a cascade of reactions toward tissue regeneration or reparative dentin formation or both. Previous reports have shown that inflammatory cytokines regulate the differentiation capacity of dental pulp stem/progenitor cells (DPCs), but none has interrogated the impact of these cytokines on the stem cell phenotype of stem/progenitor cells.
In this review, I would like to summarize about the effects of a short-term treatment with TNF-α on the stem cell phenotype and differentiation ability of human DPCs.
Journal Title
Journal of Oral Health and Biosciences
ISSN
21887888
NCID
AA12713630
Publisher
四国歯学会
Volume
28
Issue
1
Start Page
1
End Page
7
Sort Key
1
Published Date
2015-07-10
Remark
7月発行だが、6月号である。
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital