ID 110175
Title Transcription
メタボリック シンドローム ト ヒマン
Title Alternative
Metabolic syndrome and obesity
Author
Fujinaka, Yuichi Department of Medicine and Bioregulatory Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School
Keywords
metabolic syndrome
obesity
adipocyte
adipocytokine
visceral fat
Content Type
Journal Article
Description
It is well-known that obesity causes several disease, especially, cardiovascular disease. The metabolic syndrome-the cluster of obesity, impaired fasting glucose, elevated triglycerides, low high-density lipoprotein cholesterol, and hypertension, has been identified as an independent risk factor for cardiovascular disease. In this syndrome, abdominal obesity play a critical role for development of insulin resistance and atherosclerosis. Recently it is reported that visceral fat accumulation brings impaired adipocytokine environment such as increase of inflammatory cytokine and decrease of adiponectin. On the other hand, adipose tissue has an ability to activate cortisone that causes steroid excess in peripheral tissue. Though it seems to need some reevaluation, waist circumference is an useful biomarker for clinical intervention in the metabolic syndrome which aims to avoid the development of cardiovascular disease.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
63
Issue
3-4
Start Page
86
End Page
89
Sort Key
86
Published Date
2007-08-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher