ID 110175
タイトルヨミ
メタボリック シンドローム ト ヒマン
タイトル別表記
Metabolic syndrome and obesity
著者
藤中, 雄一 徳島大学大学院ヘルスバイオサイエンス研究部生体制御医学講座生体情報内科学分野
キーワード
metabolic syndrome
obesity
adipocyte
adipocytokine
visceral fat
資料タイプ
学術雑誌論文
抄録
It is well-known that obesity causes several disease, especially, cardiovascular disease. The metabolic syndrome-the cluster of obesity, impaired fasting glucose, elevated triglycerides, low high-density lipoprotein cholesterol, and hypertension, has been identified as an independent risk factor for cardiovascular disease. In this syndrome, abdominal obesity play a critical role for development of insulin resistance and atherosclerosis. Recently it is reported that visceral fat accumulation brings impaired adipocytokine environment such as increase of inflammatory cytokine and decrease of adiponectin. On the other hand, adipose tissue has an ability to activate cortisone that causes steroid excess in peripheral tissue. Though it seems to need some reevaluation, waist circumference is an useful biomarker for clinical intervention in the metabolic syndrome which aims to avoid the development of cardiovascular disease.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
63
3-4
開始ページ
86
終了ページ
89
並び順
86
発行日
2007-08-25
EDB ID
164503
フルテキストファイル
言語
jpn
著者版フラグ
出版社版