ID 110286
Title Transcription
ジュンカンキ シッカン ノ ヨボウ ト セイカツ シュウカン
Title Alternative
Lifestyle modification to prevent cardiovascular diseases
Author
Sata, Masataka Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
atherosclerosis
hypertension
dyslipidemia
diabetes
lifestyle
Content Type
Journal Article
Description
Recent evidence suggests that acute coronary syndrome(ACS)results from plaque rupture in most of the cases. Vulnerable plaques are characterized by thinning of fibrous cap, increased lipid content, decreased smooth muscle cell content, and enhanced infiltration of inflammatory cells.Coronary risk factors such as hypertension, dyslipidemia, diabetes, and smoking, promote these processes, which result in cardiovascular complications. Rigorous control of lifestyle-related diseases is important for the prevention of cardiovascular diseases.However, the molecular mechanism of plaque destabilization is not fully understood. Thus,there is no established method to predict and prevent ACS. We have been studying the pathogenesis of plaque progression and destabilization using animal models and clinical specimen.In this symposium, I will present our recent findings on the molecular mechanism of plaque rupture and discuss effective strategies to diagnose and prevent ACS.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
65
Issue
5-6
Start Page
105
End Page
110
Sort Key
105
Published Date
2009-12-20
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences