ID 110286
タイトルヨミ
ジュンカンキ シッカン ノ ヨボウ ト セイカツ シュウカン
タイトル別表記
Lifestyle modification to prevent cardiovascular diseases
著者
佐田, 政隆 徳島大学大学院ヘルスバイオサイエンス研究部器官病態修復医学講座循環器内科学分野 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
atherosclerosis
hypertension
dyslipidemia
diabetes
lifestyle
資料タイプ
学術雑誌論文
抄録
Recent evidence suggests that acute coronary syndrome(ACS)results from plaque rupture in most of the cases. Vulnerable plaques are characterized by thinning of fibrous cap, increased lipid content, decreased smooth muscle cell content, and enhanced infiltration of inflammatory cells.Coronary risk factors such as hypertension, dyslipidemia, diabetes, and smoking, promote these processes, which result in cardiovascular complications. Rigorous control of lifestyle-related diseases is important for the prevention of cardiovascular diseases.However, the molecular mechanism of plaque destabilization is not fully understood. Thus,there is no established method to predict and prevent ACS. We have been studying the pathogenesis of plaque progression and destabilization using animal models and clinical specimen.In this symposium, I will present our recent findings on the molecular mechanism of plaque rupture and discuss effective strategies to diagnose and prevent ACS.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
65
5-6
開始ページ
105
終了ページ
110
並び順
105
発行日
2009-12-20
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系