ID 110555
Title Transcription
MRI オ モチイタ ノウ キノウ タイシャ ヒョウカ ノ ケントウ ト モンダイテン
Title Alternative
Evaluation of function and metabolism of the brain using MRI
Author
Harada, Masafumi Department of Radiologic Technology, School of Health Sciences, The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
MRI
function
metabolism
BOLD
MRS
Content Type
Journal Article
Description
Several methods have been introduced in order to evaluate brain function using MRI. One is the blood oxygen level dependent (BOLD) method, which detects oxygen saturation level in a capillary region, and other is the method of flow volume measurement. Each method can detect activated regions in the brain depending on a kind of tasks and give us functional geometric information of activated brain. However, the activated pixels are not detected depending on electric activity of neurons, but the hemodynamic changes using MRI. Then there may be some cases with discrepancy between true activation of neurons and depicted activation areas by MRI. It will be important to consider difference of mechanism to depict activation when the result of functional MRI is interpreted. To evaluate metabolism in the brain, MR spectroscopy (MRS) is useful for both scientific research and clinical diagnosis. But the sensitivity of MRS is relatively lower than radioisotope methods, and our attention should be paid to maintenance of instrument condition and accuracy of the MRS measurement. MRI has huge possibility to detect function and metabolism in the brain noninvasivelly, but it will be important to understand background mechanism of used technique and avoid misinterpretation.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
58
Issue
4-5
Start Page
214
End Page
219
Sort Key
214
Published Date
2002-10-25
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences