ID 110555
タイトルヨミ
MRI オ モチイタ ノウ キノウ タイシャ ヒョウカ ノ ケントウ ト モンダイテン
タイトル別表記
Evaluation of function and metabolism of the brain using MRI
著者
原田, 雅史 徳島大学医学部保健学科診療放射線技術学講座 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
MRI
function
metabolism
BOLD
MRS
資料タイプ
学術雑誌論文
抄録
Several methods have been introduced in order to evaluate brain function using MRI. One is the blood oxygen level dependent (BOLD) method, which detects oxygen saturation level in a capillary region, and other is the method of flow volume measurement. Each method can detect activated regions in the brain depending on a kind of tasks and give us functional geometric information of activated brain. However, the activated pixels are not detected depending on electric activity of neurons, but the hemodynamic changes using MRI. Then there may be some cases with discrepancy between true activation of neurons and depicted activation areas by MRI. It will be important to consider difference of mechanism to depict activation when the result of functional MRI is interpreted. To evaluate metabolism in the brain, MR spectroscopy (MRS) is useful for both scientific research and clinical diagnosis. But the sensitivity of MRS is relatively lower than radioisotope methods, and our attention should be paid to maintenance of instrument condition and accuracy of the MRS measurement. MRI has huge possibility to detect function and metabolism in the brain noninvasivelly, but it will be important to understand background mechanism of used technique and avoid misinterpretation.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
58
4-5
開始ページ
214
終了ページ
219
並び順
214
発行日
2002-10-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系