ID 110654
Author
Satake, Nobuo Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine
Uehara, Hisanori Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sano, Nobuya Division of Surgical Pathology, University Hospital, The University of Tokushima School of Medicine
Kubo, Takayuki Division of Surgical Pathology, University Hospital, The University of Tokushima School of Medicine
Sasa, Mitsunori Tokushima Breast Care Clinic
Izumi, Keisuke Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
breast
fine-needle aspiration biopsy cytology
glycogen-rich carcinoma
c-erbB-2
cytology
Content Type
Journal Article
Description
Background : Glycogen-rich carcinoma is a rare special histologic subtype of breast cancer and its incidence is estimated to be 1.4% in breast malignancies. However, its precise characteristics in cytological specimens have not yet been fully clarified. Case : Fifty-nine-year-old and 53-year-old women underwent fine-needle aspiration biopsy cytology (FNABC) of a breast tumor, confirming malignancy. A mastectomy with axillary dissection was performed. Cytologically, a moderate amount of eosinophilic, finely granular cytoplasm was seen in the majority of the tumor cells, however, foamy and vacuolated cytoplasm was noted in some tumor cells. Histologically, the tumor cells of both cases had clear and granular cytoplasm, which showed a positive reaction with periodic acid-Schiff, eliminated by diastase. Conclusion : While clear cytoplasm in the tumor cells in the FNABC seemed to be a pivotal cytological characteristic of glycogen-rich carcinoma, it may not be a major component of cytological specimens. Routine periodic acid-Schiff staining may be required to diagnose glycogen-rich carcinoma in cytological methods.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
49
Issue
3-4
Start Page
193
End Page
196
Sort Key
193
Published Date
2002
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences