ID 110704
Author
Fujii, Masahiko Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
Miyake, Hidenori Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
Sasaki, Katsuya Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
Takagi, Toshihide Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
Takamura, Kazuhito Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
Tashiro, Seiki Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory
Keywords
pancreatic carcinoma
arterial infusion chemotherapy
liver metastases
Content Type
Journal Article
Description
Introduction : Despite various treatment trials for unresectable pancreatic carcinoma with liver metastases, the outcome has not been satisfactory. This paper reports a case of pancreatic carcinoma with multiple liver metastases that responded well to arterial infusion chemotherapy. Case report : A 65-year-old male was diagnosed with multiple liver tumors, and needle biopsy revealed adenocarcinoma. With endoscopic ultrasonography, a tumor in the pancreatic head was detected, and pancreatic carcinoma with multiple liver metastases was diagnosed. He received arterial infusion chemotherapy : cisplatin at a dose of 10mg/body/day and 500mg/body/day of 5-fluorouracil. After 14 days administration, liver metastases had decreased in number and size, but thereafter, because of hepatic arterial occlusion, the same dose of drugs was administered intravenously. The patient was discharged from the hospital and was given chemotherapy 3 days a week on an outpatient basis. Although the chemotherapy was effective, it was stopped because of severe general fatigue 5months after discharge. His general status continued to gradually worsen,and he died 12 months after diagnosis. Conclusions : Prognosis of pancreatic carcinoma with liver metastases is poor however, transarterial infusion chemotherapy may be effective to improve the prognosis and quality of life of the patients.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
50
Issue
3-4
Start Page
199
End Page
202
Sort Key
199
Published Date
2003
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences