ID 110836
Author
Takizawa, Hiromitsu Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kondo, Kazuya Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Matsuoka, Hisashi Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Uyama, Koh Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Toba, Hiroaki Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kenzaki, Koichiro Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Sakiyama, Shoji Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School KAKEN Search Researchers
Tangoku, Akira Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Miura, Kazumasa Department of Thoracic Surgery, Takamatsu Red Cross Hospital
Yoshizawa, Kiyoshi Department of Thoracic Surgery, Takamatsu Red Cross Hospital
Morita, Junji Department of Thoracic Surgery, Takamatsu Red Cross Hospital
Keywords
lung cancer surgery
mediastinal lymph node
prognosis
Content Type
Journal Article
Description
Objective : Systematic nodal dissection has been recommended for patients with resectable non-small cell lung cancer because of its staging accuracy. However, in patients with clinical stage I non-small cell lung cancer whether systematic nodal dissection provides more benefits than mediastinal lymph node sampling or not is controversial. In this retrospective study, we evaluated the effect of mediastinal lymph node sampling in patients with clinical stage I NSCLC. Methods : One hundred and nineteen consecutive patients with clinical stage I NSCLC, who underwent curative operation between January 1994 and December 2000, were retrospectively reviewed (dissection group = 58 : sampling group= 61). Systematic nodal dissection was defined as complete removal of mediastinal lymph node, and mediastinal lymph node sampling was defined as removal of lymph node levels 3, 4, and 7 for right-sided tumors and levels 5, 6, and 7 for left-sided tumors. Results : The total number of removed mediastinal lymph nodes in patients who underwent systematic nodal dissection was 22.1±9.7, which was significantly higher than that in patients who underwent mediastinal lymph node sampling of 11.4±7.0 (p<0.001). Postoperatively N2 disease was detected in 8 patients (13.8%) in the dissection group and 7 (11.5%) in the sampling group. After the median follow up of 79 months, the cancer specific survival rate at 5 year was 78.0% in the dissection group and 76.2% in the sampling group (p = 0.60). Conclusions : Mediastinal lymph node sampling showed the similar effect to systematic nodal dissection in patients with clinical stage I non-small cell lung cancer.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
55
Issue
1-2
Start Page
37
End Page
43
Sort Key
37
Published Date
2008-02
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences