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ID 110836
著者
滝沢, 宏光 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
近藤, 和也 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
マツオカ, ヒサシ Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
ウヤマ, コウ Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
鳥羽, 博明 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
監﨑, 孝一郎 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
先山, 正二 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School KAKEN研究者をさがす
丹黒, 章 Department of Oncological and Regenerative Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
ミウラ, カズマサ Department of Thoracic Surgery, Takamatsu Red Cross Hospital
ヨシザワ, キヨシ Department of Thoracic Surgery, Takamatsu Red Cross Hospital
モリタ, ジュンジ Department of Thoracic Surgery, Takamatsu Red Cross Hospital
キーワード
lung cancer surgery
mediastinal lymph node
prognosis
資料タイプ
学術雑誌論文
抄録
Objective : Systematic nodal dissection has been recommended for patients with resectable non-small cell lung cancer because of its staging accuracy. However, in patients with clinical stage I non-small cell lung cancer whether systematic nodal dissection provides more benefits than mediastinal lymph node sampling or not is controversial. In this retrospective study, we evaluated the effect of mediastinal lymph node sampling in patients with clinical stage I NSCLC. Methods : One hundred and nineteen consecutive patients with clinical stage I NSCLC, who underwent curative operation between January 1994 and December 2000, were retrospectively reviewed (dissection group = 58 : sampling group= 61). Systematic nodal dissection was defined as complete removal of mediastinal lymph node, and mediastinal lymph node sampling was defined as removal of lymph node levels 3, 4, and 7 for right-sided tumors and levels 5, 6, and 7 for left-sided tumors. Results : The total number of removed mediastinal lymph nodes in patients who underwent systematic nodal dissection was 22.1±9.7, which was significantly higher than that in patients who underwent mediastinal lymph node sampling of 11.4±7.0 (p<0.001). Postoperatively N2 disease was detected in 8 patients (13.8%) in the dissection group and 7 (11.5%) in the sampling group. After the median follow up of 79 months, the cancer specific survival rate at 5 year was 78.0% in the dissection group and 76.2% in the sampling group (p = 0.60). Conclusions : Mediastinal lymph node sampling showed the similar effect to systematic nodal dissection in patients with clinical stage I non-small cell lung cancer.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
55
1-2
開始ページ
37
終了ページ
43
並び順
37
発行日
2008-02
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系