ID | 111103 |
Title Alternative | 入院慢性腎臓病患者における血清アルブミン濃度に影響を与える因子
Serum albumin, proteinuria in hospitalized CKD patients
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Author |
Yoshimoto, Sakiya
Tokushima University
Shibata, Eriko
Tokushima University
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Ueda, Sayo
Tokushima University
Ono, Hiroyuki
Tokushima University
Nishimura, Kenji
Tokushima University
Obata, Fumiaki
Tokushima University
Inagaki, Taizo
Tokushima University
Minato, Masanori
Tokushima University
Kishi, Fumi
Tokushima University
Matsui, Naoko
Tokushima University
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Endo, Itsuro
Tokushima University
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Hann, Michael
Naval Medical Center San Diego
Doi, Toshio
Tokushima University
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Keywords | Serum albumin concentration
Proteinuria
Chronic kidney disease
Postural change
Hospitalization
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Content Type |
Thesis or Dissertation
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Description | Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n=39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient’s condition during phlebotomy.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA11166929
AA12022913
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Publisher | Faculty of Medicine Tokushima University
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Volume | 64
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Issue | 1-2
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Start Page | 146
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End Page | 152
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Sort Key | 146
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Published Date | 2017-02
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Remark | 内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨:LID201704171001.pdf 論文本文:LID201704171002.pdf 本論文は,著者Sakiya Yoshimotoの学位論文として提出され,学位審査・授与の対象となっている。 |
EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
ETD
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MEXT report number | 甲第3029号
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Diploma Number | 甲医第1333号
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Granted Date | 2017-03-23
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Degree Name |
Doctor of Medical Science
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Grantor |
Tokushima University
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departments |
University Hospital
Medical Sciences
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