ID 111103
著者
吉本, 咲耶 Tokushima University
Shibata, Eriko Tokushima University
Ueda, Sayo Tokushima University
Tamaki, Masanori Tokushima University
Nishimura, Kenji Tokushima University
Obata, Fumiaki Tokushima University
Inagaki, Taizo Tokushima University
Minato, Masanori Tokushima University
Hann, Michael Naval Medical Center San Diego
キーワード
Serum albumin concentration
Proteinuria
Chronic kidney disease
Postural change
Hospitalization
資料タイプ
学術雑誌論文
抄録
Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n=39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient’s condition during phlebotomy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
64
1-2
開始ページ
146
終了ページ
152
並び順
146
発行日
2017-02
EDB ID
329379
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系