ID 111241
Author
Keywords
genetically encoded calcium ion indicator
Ca2+ imaging
FRET
fluorescent proteins
Content Type
Journal Article
Description
Genetically encoded calcium indicators (GECIs) are powerful tools to monitor the dynamics of calcium ion (Ca2+) in living cells and organisms.With the help of GFP technology and DNA engineering, a dozen sets of GECIs have been developed so far. Their application has been widely extended into the analysis at the subcellular local, single and population of cell. In the past decades, GECIs have been dramatically improved in their performance and are becoming more and more useful for live imaging. In this review, the progress in the development of GECIs is discussed by introducing the history and emerging GECIs, which would help the selection of the appropriate GECI for a given application.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
62
Issue
1-2
Start Page
24
End Page
28
Sort Key
24
Published Date
2015-02
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences