ID 111241
著者
キーワード
genetically encoded calcium ion indicator
Ca2+ imaging
FRET
fluorescent proteins
資料タイプ
学術雑誌論文
抄録
Genetically encoded calcium indicators (GECIs) are powerful tools to monitor the dynamics of calcium ion (Ca2+) in living cells and organisms.With the help of GFP technology and DNA engineering, a dozen sets of GECIs have been developed so far. Their application has been widely extended into the analysis at the subcellular local, single and population of cell. In the past decades, GECIs have been dramatically improved in their performance and are becoming more and more useful for live imaging. In this review, the progress in the development of GECIs is discussed by introducing the history and emerging GECIs, which would help the selection of the appropriate GECI for a given application.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
62
1-2
開始ページ
24
終了ページ
28
並び順
24
発行日
2015-02
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系