ID 111882
Title Alternative
Total chemical synthesis of monoglycosylated GM2 ganglioside activator using a novel cysteine surrogate
Author
Sato, Kohei Tokushima University
Kitakaze, Keisuke Tokushima University
Nakamura, Takahiro Tokushima University
Naruse, Naoto Tokushima University
Aihara, Keisuke Tokushima University
Content Type
Journal Article
Description
We describe a novel peptide ligation/desulfurization strategy using β-mercapto-N-glycosylated asparagine derivative. The newly developed procedure is successfully applied to total chemical synthesis of GM2 ganglioside activator protein bearing a monosaccharide on the native glycosylation site.
Journal Title
Chemical Communications
ISSN
13597345
1364548X
NCID
AA11071130
Publisher
The Royal Society of Chemistry
Volume
51
Issue
49
Start Page
9946
End Page
9948
Published Date
2015-05-13
Rights
© The Royal Society of Chemistry 2015
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Pharmaceutical Sciences