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ID 114735
Title Alternative
ファロー四徴症術後患者における肺動脈弁輪及び三尖弁輪運動速度のisovolumic accelerationによる右室機能解析
IVA for RV function analysis in TOF
Author
Ono, Akemi Tokushima University
Tanaka, Manami Tokushima University
Keywords
isovolumic acceleration
right ventriclar function
pulmonary annulus
tetralogy of Fallot
Content Type
Thesis or Dissertation
Description
Assessment of right ventricular (RV) function is quite important in patients with surgically corrected tetralogy of Fallot (TOF). However, quantitative assessment of RV function remains challenging, mainly because of the complex RV geometry. This prospective study investigated isovolumic acceleration (IVA), a parameter of myocardial systolic function not influenced by either preload or afterload, using tissue Doppler imaging. We evaluated IVA measured on pulmonary annulus (PA-IVA) and tricuspid annulus (TA-IVA), because we considered that PA-IVA and TA-IVA correspond with systolic function of the RV outflow tract (RVOT) and RV basal function, respectively. Thirty-nine patients with surgically repaired TOF (TOF group) and 40 age-matched healthy children (control group) were enrolled in this study. No significant difference was seen between TA-IVA (2.5 ± 0.8 m/s2) and PA-IVA (2.4 ± 0.8 m/s2) in the control group. In the TOF group, PA-IVA (1.0 ± 0.5 m/s2) was significantly lower than TA-IVA (1.3 ± 0.6 m/s2, p < 0.05). Both TA-IVA and PA-IVA were significantly lower in the TOF group than in the control group (p < 0.05 each). We concluded that PA-IVA offers a useful index to assess RVOT function in TOF patients.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
67
Issue
1-2
Start Page
145
End Page
150
Sort Key
145
Published Date
2020-02
Remark
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Akemi Onoの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3366号
Diploma Number
甲医第1449号
Granted Date
2020-03-18
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences