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ID 114735
タイトル別表記
ファロー四徴症術後患者における肺動脈弁輪及び三尖弁輪運動速度のisovolumic accelerationによる右室機能解析
IVA for RV function analysis in TOF
著者
小野, 朱美 徳島大学大学院医科学教育部(医学専攻)
Tanaka, Manami Tokushima University
キーワード
isovolumic acceleration
right ventriclar function
pulmonary annulus
tetralogy of Fallot
資料タイプ
学位論文
抄録
Assessment of right ventricular (RV) function is quite important in patients with surgically corrected tetralogy of Fallot (TOF). However, quantitative assessment of RV function remains challenging, mainly because of the complex RV geometry. This prospective study investigated isovolumic acceleration (IVA), a parameter of myocardial systolic function not influenced by either preload or afterload, using tissue Doppler imaging. We evaluated IVA measured on pulmonary annulus (PA-IVA) and tricuspid annulus (TA-IVA), because we considered that PA-IVA and TA-IVA correspond with systolic function of the RV outflow tract (RVOT) and RV basal function, respectively. Thirty-nine patients with surgically repaired TOF (TOF group) and 40 age-matched healthy children (control group) were enrolled in this study. No significant difference was seen between TA-IVA (2.5 ± 0.8 m/s2) and PA-IVA (2.4 ± 0.8 m/s2) in the control group. In the TOF group, PA-IVA (1.0 ± 0.5 m/s2) was significantly lower than TA-IVA (1.3 ± 0.6 m/s2, p < 0.05). Both TA-IVA and PA-IVA were significantly lower in the TOF group than in the control group (p < 0.05 each). We concluded that PA-IVA offers a useful index to assess RVOT function in TOF patients.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
67
1-2
開始ページ
145
終了ページ
150
並び順
145
発行日
2020-02
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Akemi Onoの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3366号
学位記番号
甲医第1449号
学位授与年月日
2020-03-18
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系