| ID | 116787 |
| Author | |
| Keywords | HIF-PHI
CKD
anemia
iron
erythroferrone
FGF23
|
| Content Type |
Journal Article
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| Description | Hanudel et al. investigated the effects of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) on iron metabolism in a chronic kidney disease (CKD) mouse model and showed that vadadustat, an HIF-PHI, exerted beneficial effects on anemia and iron disorders independently of erythroferrone. Vadadustat also inhibited the progression of CKD and the CKD-associated increase of plasma fibroblast growth factor 23 in CKD mice. This study provides new insights into the action of HIF-PIHs in CKD.
|
| Journal Title |
Kidney International
|
| ISSN | 00852538
|
| NCID | AA00710996
AA11629608
|
| Publisher | Elsevier|International Society of Nephrology
|
| Volume | 100
|
| Issue | 1
|
| Start Page | 14
|
| End Page | 16
|
| Published Date | 2021-06-18
|
| Rights | © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
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| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
|
| TextVersion |
Author
|
| departments |
Medical Sciences
|
