| ID | 116787 |
| 著者 | |
| キーワード | HIF-PHI
CKD
anemia
iron
erythroferrone
FGF23
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | Hanudel et al. investigated the effects of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) on iron metabolism in a chronic kidney disease (CKD) mouse model and showed that vadadustat, an HIF-PHI, exerted beneficial effects on anemia and iron disorders independently of erythroferrone. Vadadustat also inhibited the progression of CKD and the CKD-associated increase of plasma fibroblast growth factor 23 in CKD mice. This study provides new insights into the action of HIF-PIHs in CKD.
|
| 掲載誌名 |
Kidney International
|
| ISSN | 00852538
|
| cat書誌ID | AA00710996
AA11629608
|
| 出版者 | Elsevier|International Society of Nephrology
|
| 巻 | 100
|
| 号 | 1
|
| 開始ページ | 14
|
| 終了ページ | 16
|
| 発行日 | 2021-06-18
|
| 権利情報 | © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
医学系
|
