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ID 119382
Title Alternative
胃がん患者における嗅覚変化が胃切除後の体重減少に与える影響
Author
Matsuo, Hiromi Tokushima University|Cancer Institute Hospital of JFCR
Matsui, Ryota Cancer Institute Hospital of JFCR
Kumagai, Koshi Cancer Institute Hospital of JFCR|Kitasato University
Ida, Satoshi Cancer Institute Hospital of JFCR|Kumamoto University
Saino, Yoko Tokushima University|Cancer Institute Hospital of JFCR
Fujihara, Aya Cancer Institute Hospital of JFCR
Takagi, Kumi Cancer Institute Hospital of JFCR
Itami, Yukiko Cancer Institute Hospital of JFCR
Ishii, Misuzu Cancer Institute Hospital of JFCR
Moriya, Naoki Cancer Institute Hospital of JFCR
Izumi-Mishima, Yuna Tokushima University
Nomura, Kazuhiro Tokushima University
Nunobe, Souya Cancer Institute Hospital of JFCR
Keywords
olfaction
gastric cancer
gastrectomy
body weight loss
smell
Content Type
Thesis or Dissertation
Description
Patients undergoing gastrectomy for gastric cancer may experience alterations in olfaction, yet the association between olfactory changes and postoperative weight loss remains uncertain. This study aimed to elucidate the relationship between olfactory changes and postoperative weight loss in patients with gastric cancer. Patients who underwent radical gastrectomy for gastric cancer between February 2022 and August 2022 were included in the study. Those experiencing a higher Visual Analog Scale (VAS) score postoperatively compared to preoperatively were deemed to have undergone olfactory changes. Postoperative weight loss was determined using the 75th percentile as a cutoff value, designating patients surpassing this threshold as experiencing significant weight loss. Multivariate logistic regression analysis was employed to identify risk factors for postoperative weight loss, with statistical significance set at p < 0.05. Out of 58 patients, 10 (17.2%) exhibited olfactory changes. The rate of postoperative weight loss at one month was markedly higher in the group with olfactory changes compared to those without (9.6% versus 6.2%, respectively; p = 0.002). In addition, the group experiencing olfactory changes demonstrated significantly lower energy intake compared to the group without such changes (1050 kcal versus 1250 kcal, respectively; p = 0.029). Logistic regression analysis revealed olfactory changes as an independent risk factor for significant weight loss at one month postoperatively (odds ratio: 7.64, 95% confidence interval: 1.09–71.85, p = 0.048). In conclusion, olfactory changes emerged as an independent risk factor for postoperative weight loss at one month in patients with gastric cancer following gastrectomy.
Journal Title
Nutrients
ISSN
20726643
Publisher
MDPI
Volume
16
Issue
6
Start Page
851
Published Date
2024-03-15
Remark
内容要旨・審査要旨・論文本文の公開
本論文は,著者Hiromi Matsuoの学位論文として提出され,学位審査・授与の対象となっている。
Rights
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3829号
Diploma Number
甲栄第308号
Granted Date
2024-04-25
Degree Name
Doctor of Nutritional Science
Grantor
Tokushima University
departments
Medical Sciences