ID | 119382 |
Title Alternative | 胃がん患者における嗅覚変化が胃切除後の体重減少に与える影響
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Author |
Matsuo, Hiromi
Tokushima University|Cancer Institute Hospital of JFCR
Matsui, Ryota
Cancer Institute Hospital of JFCR
Kumagai, Koshi
Cancer Institute Hospital of JFCR|Kitasato University
Ida, Satoshi
Cancer Institute Hospital of JFCR|Kumamoto University
Saino, Yoko
Tokushima University|Cancer Institute Hospital of JFCR
Fujihara, Aya
Cancer Institute Hospital of JFCR
Takagi, Kumi
Cancer Institute Hospital of JFCR
Itami, Yukiko
Cancer Institute Hospital of JFCR
Ishii, Misuzu
Cancer Institute Hospital of JFCR
Moriya, Naoki
Cancer Institute Hospital of JFCR
Izumi-Mishima, Yuna
Tokushima University
Nomura, Kazuhiro
Tokushima University
Nunobe, Souya
Cancer Institute Hospital of JFCR
Tsutsumi, Rie
Tokushima University|Hiroshima University
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Keywords | olfaction
gastric cancer
gastrectomy
body weight loss
smell
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Content Type |
Thesis or Dissertation
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Description | Patients undergoing gastrectomy for gastric cancer may experience alterations in olfaction, yet the association between olfactory changes and postoperative weight loss remains uncertain. This study aimed to elucidate the relationship between olfactory changes and postoperative weight loss in patients with gastric cancer. Patients who underwent radical gastrectomy for gastric cancer between February 2022 and August 2022 were included in the study. Those experiencing a higher Visual Analog Scale (VAS) score postoperatively compared to preoperatively were deemed to have undergone olfactory changes. Postoperative weight loss was determined using the 75th percentile as a cutoff value, designating patients surpassing this threshold as experiencing significant weight loss. Multivariate logistic regression analysis was employed to identify risk factors for postoperative weight loss, with statistical significance set at p < 0.05. Out of 58 patients, 10 (17.2%) exhibited olfactory changes. The rate of postoperative weight loss at one month was markedly higher in the group with olfactory changes compared to those without (9.6% versus 6.2%, respectively; p = 0.002). In addition, the group experiencing olfactory changes demonstrated significantly lower energy intake compared to the group without such changes (1050 kcal versus 1250 kcal, respectively; p = 0.029). Logistic regression analysis revealed olfactory changes as an independent risk factor for significant weight loss at one month postoperatively (odds ratio: 7.64, 95% confidence interval: 1.09–71.85, p = 0.048). In conclusion, olfactory changes emerged as an independent risk factor for postoperative weight loss at one month in patients with gastric cancer following gastrectomy.
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Journal Title |
Nutrients
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ISSN | 20726643
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Publisher | MDPI
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Volume | 16
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Issue | 6
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Start Page | 851
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Published Date | 2024-03-15
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Remark | 内容要旨・審査要旨・論文本文の公開
本論文は,著者Hiromi Matsuoの学位論文として提出され,学位審査・授与の対象となっている。 |
Rights | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
ETD
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MEXT report number | 甲第3829号
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Diploma Number | 甲栄第308号
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Granted Date | 2024-04-25
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Degree Name |
Doctor of Nutritional Science
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Grantor |
Tokushima University
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departments |
Medical Sciences
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