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ID 119382
タイトル別表記
胃がん患者における嗅覚変化が胃切除後の体重減少に与える影響
著者
松尾, 宏美 徳島大学大学院医科栄養学研究科(医科栄養学専攻)
Matsui, Ryota Cancer Institute Hospital of JFCR
Kumagai, Koshi Cancer Institute Hospital of JFCR|Kitasato University
Ida, Satoshi Cancer Institute Hospital of JFCR|Kumamoto University
Saino, Yoko Tokushima University|Cancer Institute Hospital of JFCR
Fujihara, Aya Cancer Institute Hospital of JFCR
Takagi, Kumi Cancer Institute Hospital of JFCR
Itami, Yukiko Cancer Institute Hospital of JFCR
Ishii, Misuzu Cancer Institute Hospital of JFCR
Moriya, Naoki Cancer Institute Hospital of JFCR
Izumi-Mishima, Yuna Tokushima University
野村, 和弘 Tokushima University
Nunobe, Souya Cancer Institute Hospital of JFCR
キーワード
olfaction
gastric cancer
gastrectomy
body weight loss
smell
資料タイプ
学位論文
抄録
Patients undergoing gastrectomy for gastric cancer may experience alterations in olfaction, yet the association between olfactory changes and postoperative weight loss remains uncertain. This study aimed to elucidate the relationship between olfactory changes and postoperative weight loss in patients with gastric cancer. Patients who underwent radical gastrectomy for gastric cancer between February 2022 and August 2022 were included in the study. Those experiencing a higher Visual Analog Scale (VAS) score postoperatively compared to preoperatively were deemed to have undergone olfactory changes. Postoperative weight loss was determined using the 75th percentile as a cutoff value, designating patients surpassing this threshold as experiencing significant weight loss. Multivariate logistic regression analysis was employed to identify risk factors for postoperative weight loss, with statistical significance set at p < 0.05. Out of 58 patients, 10 (17.2%) exhibited olfactory changes. The rate of postoperative weight loss at one month was markedly higher in the group with olfactory changes compared to those without (9.6% versus 6.2%, respectively; p = 0.002). In addition, the group experiencing olfactory changes demonstrated significantly lower energy intake compared to the group without such changes (1050 kcal versus 1250 kcal, respectively; p = 0.029). Logistic regression analysis revealed olfactory changes as an independent risk factor for significant weight loss at one month postoperatively (odds ratio: 7.64, 95% confidence interval: 1.09–71.85, p = 0.048). In conclusion, olfactory changes emerged as an independent risk factor for postoperative weight loss at one month in patients with gastric cancer following gastrectomy.
掲載誌名
Nutrients
ISSN
20726643
出版者
MDPI
16
6
開始ページ
851
発行日
2024-03-15
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Hiromi Matsuoの学位論文として提出され,学位審査・授与の対象となっている。
権利情報
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3829号
学位記番号
甲栄第308号
学位授与年月日
2024-04-25
学位名
博士(栄養学)
学位授与機関
徳島大学
部局
医学系