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ID 113515
Author
Tanaka, Masaki The University of Tokushima
Adzuma, Kyo The University of Tokushima
Iwami, Miki The University of Tokushima
Keywords
Human calgizzarin
Random cDNA sequencing
Content Type
Journal Article
Description
A cDNA library was constructed from COLO 205 and 1056 clones randomly selected from this library were partially sequenced. Two hundred and two (38.4%) out of 526 independent genes had more than 80% similarity to the genes reported in GenBank. In Northern blot analysis, 96 out of 98 genes were shown to be expressed at the same level in colon and lung carcinoma cell lines and control fibroblasts. Only two clones, including human synovial phospholipase A-2 and a homologue to rabbit calgizzarin, were expressed at different levels among these cell lines. The full sequence of human calgizzarin was determined and its expression was remarkably elevated in colorectal cancers compared with that in normal colorectal mucosa.
Journal Title
Cancer Letters
ISSN
03043835
NCID
AA00598513
AA1152274X
Publisher
Elsevier
Volume
89
Issue
2
Start Page
195
End Page
200
Published Date
1995-03-02
Remark
本論文は,著者Masaki Tanakaの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Oral Sciences
Medical Sciences
Institute of Advanced Medical Sciences