ID | 113515 |
Author |
Tanaka, Masaki
The University of Tokushima
Adzuma, Kyo
The University of Tokushima
Iwami, Miki
The University of Tokushima
Yoshimoto, Katsuhiko
The University of Tokushima
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Itakura, Mitsuo
The University of Tokushima
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Keywords | Human calgizzarin
Random cDNA sequencing
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Content Type |
Journal Article
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Description | A cDNA library was constructed from COLO 205 and 1056 clones randomly selected from this library were partially sequenced. Two hundred and two (38.4%) out of 526 independent genes had more than 80% similarity to the genes reported in GenBank. In Northern blot analysis, 96 out of 98 genes were shown to be expressed at the same level in colon and lung carcinoma cell lines and control fibroblasts. Only two clones, including human synovial phospholipase A-2 and a homologue to rabbit calgizzarin, were expressed at different levels among these cell lines. The full sequence of human calgizzarin was determined and its expression was remarkably elevated in colorectal cancers compared with that in normal colorectal mucosa.
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Journal Title |
Cancer Letters
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ISSN | 03043835
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NCID | AA00598513
AA1152274X
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Publisher | Elsevier
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Volume | 89
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Issue | 2
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Start Page | 195
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End Page | 200
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Published Date | 1995-03-02
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Remark | 本論文は,著者Masaki Tanakaの学位論文として提出され,学位審査・授与の対象となっている。
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DOI (Published Version) | |
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language |
eng
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TextVersion |
Publisher
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departments |
Oral Sciences
Medical Sciences
Institute of Advanced Medical Sciences
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