ID | 113515 |
著者 |
Tanaka, Masaki
The University of Tokushima
Adzuma, Kyo
The University of Tokushima
Iwami, Miki
The University of Tokushima
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キーワード | Human calgizzarin
Random cDNA sequencing
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資料タイプ |
学術雑誌論文
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抄録 | A cDNA library was constructed from COLO 205 and 1056 clones randomly selected from this library were partially sequenced. Two hundred and two (38.4%) out of 526 independent genes had more than 80% similarity to the genes reported in GenBank. In Northern blot analysis, 96 out of 98 genes were shown to be expressed at the same level in colon and lung carcinoma cell lines and control fibroblasts. Only two clones, including human synovial phospholipase A-2 and a homologue to rabbit calgizzarin, were expressed at different levels among these cell lines. The full sequence of human calgizzarin was determined and its expression was remarkably elevated in colorectal cancers compared with that in normal colorectal mucosa.
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掲載誌名 |
Cancer Letters
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ISSN | 03043835
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cat書誌ID | AA00598513
AA1152274X
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出版者 | Elsevier
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巻 | 89
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号 | 2
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開始ページ | 195
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終了ページ | 200
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発行日 | 1995-03-02
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備考 | 本論文は,著者Masaki Tanakaの学位論文として提出され,学位審査・授与の対象となっている。
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言語 |
eng
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著者版フラグ |
出版社版
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部局 |
歯学系
医学系
先端酵素学研究所
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