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ID 115959
Author
Keywords
Type 2 diabetes mellitus
Non-alcoholic fatty liver disease
Dipeptidyl-peptidase 4 inhibitors
Agonist obeticholic acid
Content Type
Journal Article
Description
The combination of Type 2 Diabetes Mellitus (T2DM) and Non-Alcoholic Fatty Liver Disease (NAFLD) has been a crucial problem. NAFLD means wide from Hepatic Steatosis (HS) to Nonalcoholic Steatohepatitis (NASH). NAFLD may be the predictor of causing Cardiovascular Disease (CVD). A dynamic association is found between NAFLD and Hepatic Insulin Resistance (IR). Treatments for T2DM and NAFLD include Glucagon-Like Peptide 1 Receptor Agonist (GLP-1 RA), Dipeptidyl-Peptidase 4 Inhibitors (DPP-4i) and Sodium-Glucose Cotransporter 2 inhibitors (SGLT2i). An advanced NASH-specific agent is the Farnesoid X Receptor (FXR) agonist Obeticholic Acid (OCA). Further development of research and pharmaceutical industry will be expected.
Journal Title
Edelweiss Journal of Biomedical Research and Review
ISSN
26902613
Publisher
Edelweiss Publications
Volume
3
Issue
1
Start Page
9
End Page
11
Published Date
2021-04-28
Rights
This is an open-access article distributed under the terms of the Creative Commons Attribution License(https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DOI (Published Version)
URL ( Publisher's Version )
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language
eng
TextVersion
Publisher
departments
Medical Sciences