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  2. Hiasa, Masahiro

Hiasa, Masahiro

Diploma Number (asc)
TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects
Author Tenshin, Hirofumi/ Teramachi, Jumpei/ Oda, Asuka/ Amachi, Ryota/ Hiasa, Masahiro/ Bat-Erdene, Ariunzaya/ Watanabe, Keiichiro/ Iwasa, Masami/ Harada, Takeshi/ Fujii, Shiroh/ Kagawa, Kumiko/ Sogabe, Kimiko/ Nakamura, Shingen/ Miki, Hirokazu/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Aihara, Kenichi/ Endo, Itsuro/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Blood Advances
Volume 1
Issue 24
Published Date 2017-10-26
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis : Suppressive Effects of Febuxostat
Author Ashtar, Mohannad/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Bat-Erdene, Ariunzaya/ Hiasa, Masahiro/ Oda, Asuka/ Tanimoto, Kotaro/ Shimizu, So/ Higa, Yoshiki/ Harada, Takeshi/ Oura, Masahiro/ Sogabe, Kimiko/ Nakamura, Shingen/ Fujii, Shiro/ Sumitani, Ryohei/ Miki, Hirokazu/ Udaka, Kengo/ Takahashi, Mamiko/ Kagawa, Kumiko/ Endo, Itsuro/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Cancers
Volume 12
Issue 4
Published Date 2020-04-09
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Mechanical unloading aggravates bone destruction and tumor expansion in myeloma
Author Tanimoto, Kotaro/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Oda, Asuka/ Harada, Takeshi/ Higa, Yoshiki/ Sogabe, Kimiko/ Oura, Masahiro/ Sumitani, Ryohei/ Hara, Tomoyo/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Haematologica
Volume 107
Issue 3
Published Date 2021-11-18
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Aberrant upregulation of the endogenous PP2A inhibitor CIP2A is vital for myeloma cell growth and survival
Author Shimizu, So/ Teramachi, Jumpei/ Harada, Takeshi/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Oda, Asuka/ Seki, Aiko/ Inoue, Yusuke/ Tanimoto, Kotaro/ Higa, Yoshiki/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Sawa, Yoshihiko/ Endo, Itsuro/ Tsuneyama, Koichi/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Myeloma
Volume 12
Issue 2
Published Date 2022
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2
Author Higa, Yoshiki/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Nakaue, Emiko/ Tanaka, Mariko/ Kim, Sooha/ Nakagawa, Motosumi/ Shimizu, So/ Tanimoto, Kotaro/ Teramachi, Jumpei/ Harada, Takeshi/ Oda, Asuka/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Antioxidants
Volume 12
Issue 1
Published Date 2023-01-05
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors
Author Nakaue, Emiko/ Teramachi, Jumpei/ Tenshin, Hirofumi/ Hiasa, Masahiro/ Harada, Takeshi/ Oda, Asuka/ Inoue, Yusuke/ Shimizu, So/ Higa, Yoshiki/ Sogabe, Kimiko/ Oura, Masahiro/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Endo, Itsuro/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Hematology
Volume 118
Issue 1
Published Date 2023-04-11
departments Oral Sciences University Hospital Medical Sciences
Activating transcription factor 4, an ER stress mediator , is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib
Author Nakamura, Shingen/ Miki, Hirokazu/ Kido, Shinsuke/ Nakano, Ayako/ Hiasa, Masahiro/ Oda, Asuka/ Amou, Hiroe/ Watanabe, Keiichiro/ Harada, Takeshi/ Fujii, Shiro/ Takeuchi, Kyoko/ Kagawa, Kumiko/ Ozaki, Shuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Hematology
Volume 98
Issue 1
Published Date 2013-05-25
departments Medical Sciences University Hospital Oral Sciences Institute of Advanced Medical Sciences
The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells
Author Asano, Jin/ Nakano, Ayako/ Oda, Asuka/ Amou, Hiroe/ Hiasa, Masahiro/ Takeuchi, Kyoko/ Miki, Hirokazu/ Nakamura, Shingen/ Harada, Takeshi/ Fujii, Shiro/ Kagawa, Kumiko/ Endo, Itsuro/ Yata, Kenichiro/ Sakai, Akira/ Ozaki, Shuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Leukemia
Volume 25
Issue 7
Published Date 2011-04-08
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation
Author Hanson, Derek James/ Nakamura, Shingen/ Amachi, Ryota/ Hiasa, Masahiro/ Oda, Asuka/ Tsuji, Daisuke/ Itoh, Kohji/ Harada, Takeshi/ Horikawa, Kazuki/ Teramachi, Jumpei/ Miki, Hirokazu/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Oncotarget
Volume 6
Issue 32
Published Date 2015-09-10
departments Medical Sciences Oral Sciences Pharmaceutical Sciences University Hospital Institute of Advanced Medical Sciences
Synergistic targeting of Sp1, a critical transcription factor for myeloma cell growth and survival, by panobinostat and proteasome inhibitors
Author Bat-Erdene, Ariunzaya/ Miki, Hirokazu/ Oda, Asuko/ Nakamura, Shingen/ Teramachi, Jumpei/ Amachi, Ryota/ Tenshin, Hirofumi/ Hiasa, Masahiro/ Iwasa, Masami/ Harada, Takeshi/ Fujii, Shiroh/ Sogabe, Kimiko/ Kagawa, Kumiko/ Yoshida, Sumiko/ Endo, Itsuro/ Aihara, Kenichi/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Oncotarget
Volume 7
Issue 48
Published Date 2016-10-12
departments University Hospital Medical Sciences Oral Sciences
Unique anti-myeloma activity by thiazolidine-2,4-dione compounds with Pim inhibiting activity
Author Fujii, Shiro/ Nakamura, Shingen/ Oda, Asuka/ Miki, Hirokazu/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Hiasa, Masahiro/ Bat-Erdene, Ariunzaya/ Maeda, Yusaku/ Oura, Masahiro/ Takahashi, Mamiko/ Iwasa, Masami/ Endo, Itsuro/ Yoshida, Sumiko/ Aihara, Ken-ichi/ Kurahashi, Kiyoe/ Harada, Takeshi/ Kagawa, Kumiko/ Nakao, Michiyasu/ Sano, Shigeki/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title British Journal of Haematology
Volume 180
Issue 2
Published Date 2018-01-12
departments University Hospital Medical Sciences Oral Sciences Pharmaceutical Sciences
Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors
Author Sogabe, Kimiko/ Nakamura, Shingen/ Higa, Yoshiki/ Miki, Hirokazu/ Oda, Asuka/ Maruhashi, Tomoko/ Sumitani, Ryohei/ Oura, Masahiro/ Takahashi, Mamiko/ Nakamura, Masafumi/ Maeda, Yusaku/ Hara, Tomoyo/ Yamagami, Hiroki/ Fujii, Shiro/ Kagawa, Kumiko/ Ozaki, Shuji/ Kurahashi, Kiyoe/ Endo, Itsuro/ Aihara, Ken-ichi/ Nakaue, Emiko/ Hiasa, Masahiro/ Teramachi, Jumpei/ Harada, Takeshi/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Hematology
Volume 119
Issue 3
Published Date 2024-01-21
departments Medical Sciences University Hospital Oral Sciences
Pathogenesis and treatment of multiple myeloma bone disease
Author Hiasa, Masahiro/ Harada, Takeshi/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Journal Article
Journal Title Japanese Dental Science Review
Volume 57
Published Date 2021-09-23
departments Oral Sciences University Hospital Medical Sciences
Long-term Management of a Patient with Apert Syndrome
Author Horiuchi, Shinya/ Sato, Hiroko/ Iwasa, Akihiko/ Ichihara, Aki/ Tenshin, Hirofumi/ Watanabe, Keiichiro/ Hiasa, Masahiro/ Hashimoto, Ichiro/ Tanaka, Eiji/
Content Type Journal Article
Journal Title The Journal of Contemporary Dental Practice
Volume 22
Issue 10
Published Date 2021-10
departments University Hospital Oral Sciences Medical Sciences
TGF-β-activated kinase-1 inhibitor LL-Z1640-2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF-α and RANKL expression
Author Tenshin, Hirofumi/ Teramachi, Jumpei/ Ashtar, Mohannad/ Hiasa, Masahiro/ Inoue, Yusuke/ Oda, Asuka/ Tanimoto, Kotaro/ Shimizu, So/ Higa, Yoshiki/ Harada, Takeshi/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Sebe, Mayu/ Tsutsumi, Rie/ Sakaue, Hiroshi/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Journal Article
Journal Title Clinical & Translational Immunology
Volume 11
Issue 1
Published Date 2022-01-19
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Myeloma–Bone Interaction : A Vicious Cycle via TAK1–PIM2 Signaling
Author Harada, Takeshi/ Hiasa, Masahiro/ Teramachi, Jumpei/ Abe, Masahiro/
Content Type Journal Article
Journal Title Cancers
Volume 13
Issue 17
Published Date 2021-09-03
departments University Hospital Oral Sciences Medical Sciences
Nonsurgical orthodontic treatment for a patient with Sotos syndrome
Author Shioyasono, Ryoko/ Yoshinaga, Kaoru/ Shioyasono, Atsushi/ Ito, Ayami/ Watanabe, Keiichiro/ Hiasa, Masahiro/ Horiuchi, Shinya/ Tanaka, Eiji/
Content Type Journal Article
Journal Title American Journal of Orthodontics and Dentofacial Orthopedics
Volume 163
Issue 3
Published Date 2022-11-24
departments Oral Sciences University Hospital
Lactate secreted via MCT4 from bone‑colonizing breast cancer excites sensory neurons via GPR81
Author Okui, Tatsuo/ Hiasa, Masahiro/ Hasegawa, Kazuaki/ Nakamura, Tomoya/ Ono, Kisho/ Ibaragi, Soichiro/ Kanno, Takahiro/ Sasaki, Akira/ Yoneda, Toshiyuki/
Content Type Journal Article
Journal Title International Journal of Oncology
Volume 62
Issue 3
Published Date 2023-02-08
departments Oral Sciences
Sensory nerves : A driver of the vicious cycle in bone metastasis?
Author Yoneda, Toshiyuki/ Hiasa, Masahiro/ Okui, Tatsuo/ Hata, Kenji/
Content Type Journal Article
Journal Title Journal of Bone Oncology
Volume 30
Published Date 2021-08-25
departments Oral Sciences
Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis
Author Dong, Bingzi/ Hiasa, Masahiro/ Higa, Yoshiki/ Ohnishi, Yukiyo/ Endo, Itsuro/ Kondo, Takeshi/ Takashi, Yuichi/ Tsoumpra, Maria/ Kainuma, Risa/ Sawatsubashi, Shun/ Kiyonari, Hiroshi/ Shioi, Go/ Sakaue, Hiroshi/ Nakashima, Tomoki/ Kato, Shigeaki/ Abe, Masahiro/ Fukumoto, Seiji/ Matsumoto, Toshio/
Content Type Journal Article
Journal Title Nature Communications
Volume 13
Published Date 2022-11-23
departments Oral Sciences Medical Sciences University Hospital Institute of Advanced Medical Sciences
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