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ID 114639
Title Alternative
かに爪様徴候 : 脳主幹動脈閉塞に対する血栓回収療法後の血管造影上の再開通予測因子
AN ANGIOGRAPHICAL PREDICTOR FOR SUCCESSFUL RECANALIZATION
Author
Korai, Masaaki Tokushima University
Keywords
mechanical thrombectomy
angiography
recanalization
large vessel occlusion
Content Type
Thesis or Dissertation
Description
Background: Mechanical thrombectomy undoubtedly improves functional outcomes for patients with acute ischemic stroke. Although we have observed occlusion sites that protrude proximally into the vessel on angiography, termed the “claw sign,” we have been unable to state its clinical significance. In this study, we aimed to determine whether the presence of a claw sign was related to recanalization success after mechanical thrombectomy. Materials and Methods: We retrospectively included 73 consecutive patients treated for acute cerebral large vessel occlusion by mechanical thrombectomy between January 2014 and December 2017. The angiographic claw sign was defined as a thrombus that protruded proximally by more than half the diameter of the parent artery. Claw sign positivity, clinical and etiological features, and outcomes were compared between groups with and without recanalization. Results: The claw sign was observed in 29 of 73 (40%) patients and was positive significantly more frequently in those with recanalization (50.0%) than in those without recanalization (5.9%) (P < .01). By multivariate analysis, the claw sign was the only pretreatment parameter to predict successful recanalization (odds ratio, 12.50; 95% confidence interval, 1.50-103.00; P = .019). Conclusions: The presence of the claw sign might predict successful recanalization in patients undergoing mechanical thrombectomy for large vessel occlusion.
Journal Title
Journal of Stroke and Cerebrovascular Diseases
ISSN
10523057
15328511
NCID
AA11543284
Publisher
Elsevier
Volume
28
Issue
6
Start Page
1555
End Page
1560
Published Date
2019-03-28
Remark
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Yuki Yamamotoの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3367号
Diploma Number
甲医第1450号
Granted Date
2020-03-18
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences
University Hospital