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タイトル別表記
かに爪様徴候 : 脳主幹動脈閉塞に対する血栓回収療法後の血管造影上の再開通予測因子
AN ANGIOGRAPHICAL PREDICTOR FOR SUCCESSFUL RECANALIZATION
著者
山本, 雄貴 徳島大学大学院医科学教育部(医学専攻) 徳島大学 教育研究者総覧
高麗, 雅章 Tokushima University
キーワード
mechanical thrombectomy
angiography
recanalization
large vessel occlusion
資料タイプ
学位論文
抄録
Background: Mechanical thrombectomy undoubtedly improves functional outcomes for patients with acute ischemic stroke. Although we have observed occlusion sites that protrude proximally into the vessel on angiography, termed the “claw sign,” we have been unable to state its clinical significance. In this study, we aimed to determine whether the presence of a claw sign was related to recanalization success after mechanical thrombectomy. Materials and Methods: We retrospectively included 73 consecutive patients treated for acute cerebral large vessel occlusion by mechanical thrombectomy between January 2014 and December 2017. The angiographic claw sign was defined as a thrombus that protruded proximally by more than half the diameter of the parent artery. Claw sign positivity, clinical and etiological features, and outcomes were compared between groups with and without recanalization. Results: The claw sign was observed in 29 of 73 (40%) patients and was positive significantly more frequently in those with recanalization (50.0%) than in those without recanalization (5.9%) (P < .01). By multivariate analysis, the claw sign was the only pretreatment parameter to predict successful recanalization (odds ratio, 12.50; 95% confidence interval, 1.50-103.00; P = .019). Conclusions: The presence of the claw sign might predict successful recanalization in patients undergoing mechanical thrombectomy for large vessel occlusion.
掲載誌名
Journal of Stroke and Cerebrovascular Diseases
ISSN
10523057
15328511
cat書誌ID
AA11543284
出版者
Elsevier
28
6
開始ページ
1555
終了ページ
1560
発行日
2019-03-28
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Yuki Yamamotoの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3367号
学位記番号
甲医第1450号
学位授与年月日
2020-03-18
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
病院