拡張型心筋症を伴った中毒性多結節性甲状腺腫の1例

A woman in her 80s who was diagnosed with multiple thyroid tumors and subclinical hyperthyroidism 1 year previously was referred to our outpatient clinic due to deteriorated hyperthyroidism. She was diagnosed with dilated cardiomyopathy 4 years ago. Her cardiac function has been stabilized with medical conservative treatment. Blood autoantibody levels, including TSAb and TRAb, were within normal ranges. Ultrasonography and computed tomography revealed multiple tumor lesions in both thyroid lobes. Tc-99m scintigraphy showed multiple hot nodules in both thyroid lobes. Because the patient’s thyroid function had deteriorated, we selected surgical total thyroidectomy rather than radioisotope treatment as the most appropriate treatment. Histopathological examination of the resected specimen demonstrated multiple nodular lesions with a maximum size of 23 mm and a microlesion of papillary carcinoma 2 mm in diameter in the thyroid. A few days after surgery, thyroid function blood levels declined to the normal range.