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ID 116057
Title Alternative
求心性の歯周組織感覚入力により誘発された前頭前野の活動は咬合力を抑制する
Author
Keywords
Prefrontal cortex
Periodontal afferent inputs
Functional near-infrared spectroscopy
Occlusal force
Content Type
Thesis or Dissertation
Description
The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships between periodontal sensation, PFC activity, and the performance of motor tasks, have not been evaluated in detail. Therefore, using functional near-infrared spectroscopy, we investigated PFC activity by monitoring changes in cerebral blood flow (CBF) to specific areas of the PFC that corresponded to changes in occlusal force generated during 4 different biting tasks: 1) occlusion with the central incisor with an interocclusal distance of 5 mm (BI-5 mm); or 2) 10 mm (BI-10 mm); 3) occlusion with the first molars with an interocclusal distance of 5 mm (BM-5 mm), or 4) 10 mm (BM-10 mm). Occlusion of molars generated increased PFC regional CBF as the interocclusal distance decreased (BM-10 mm vs BM-5 mm). No significant differences in CBF during occlusion of incisors were found when comparing 5 mm and 10 mm intercostal distances (BI-5 mm vs BI-10 mm). The mean occlusal force generated by BM-5 mm occlusion was significantly lower than that generated by BM-10 mm occlusion. Taken together, our results suggest that the PFC decreases efferent signaling to motor units, to reduce occlusal force generated when periodontal sensation, which is greater when the interocclusal distance is reduced, is primarily responsible for maintaining occlusal force in the absence of sensations from the temporomandibular joint and muscle spindles.
Journal Title
Experimental Brain Research
ISSN
00144819
14321106
NCID
AA00640970
Publisher
Springer Nature
Volume
237
Issue
11
Start Page
2767
End Page
2774
Published Date
2019-08-22
Remark
内容要旨・審査要旨・論文本文の公開
本論文は,著者Takahiro Kishimotoの学位論文として提出され,学位審査・授与の対象となっている。
This is a post-peer-review, pre-copyedit version of an article published in Experimental Brain Research. The final authenticated version is available online at: https://doi.org/10.1007/s00221-019-05630-y
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3491号
Diploma Number
甲口第469号
Granted Date
2021-03-23
Degree Name
Doctor of Dental Science
Grantor
Tokushima University
departments
University Hospital
Oral Sciences