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ID 116057
タイトル別表記
求心性の歯周組織感覚入力により誘発された前頭前野の活動は咬合力を抑制する
著者
岸本, 卓大 徳島大学大学院口腔科学教育部(口腔科学専攻) 徳島大学 教育研究者総覧
キーワード
Prefrontal cortex
Periodontal afferent inputs
Functional near-infrared spectroscopy
Occlusal force
資料タイプ
学位論文
抄録
The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships between periodontal sensation, PFC activity, and the performance of motor tasks, have not been evaluated in detail. Therefore, using functional near-infrared spectroscopy, we investigated PFC activity by monitoring changes in cerebral blood flow (CBF) to specific areas of the PFC that corresponded to changes in occlusal force generated during 4 different biting tasks: 1) occlusion with the central incisor with an interocclusal distance of 5 mm (BI-5 mm); or 2) 10 mm (BI-10 mm); 3) occlusion with the first molars with an interocclusal distance of 5 mm (BM-5 mm), or 4) 10 mm (BM-10 mm). Occlusion of molars generated increased PFC regional CBF as the interocclusal distance decreased (BM-10 mm vs BM-5 mm). No significant differences in CBF during occlusion of incisors were found when comparing 5 mm and 10 mm intercostal distances (BI-5 mm vs BI-10 mm). The mean occlusal force generated by BM-5 mm occlusion was significantly lower than that generated by BM-10 mm occlusion. Taken together, our results suggest that the PFC decreases efferent signaling to motor units, to reduce occlusal force generated when periodontal sensation, which is greater when the interocclusal distance is reduced, is primarily responsible for maintaining occlusal force in the absence of sensations from the temporomandibular joint and muscle spindles.
掲載誌名
Experimental Brain Research
ISSN
00144819
14321106
cat書誌ID
AA00640970
出版者
Springer Nature
237
11
開始ページ
2767
終了ページ
2774
発行日
2019-08-22
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Takahiro Kishimotoの学位論文として提出され,学位審査・授与の対象となっている。
This is a post-peer-review, pre-copyedit version of an article published in Experimental Brain Research. The final authenticated version is available online at: https://doi.org/10.1007/s00221-019-05630-y
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3491号
学位記番号
甲口第469号
学位授与年月日
2021-03-23
学位名
博士(歯学)
学位授与機関
徳島大学
部局
病院
歯学系