ID | 97534 |
Title Transcription | サイキン カンセンショウ カンジャ ニオケル スタチン ノ タメンテキ コウカ
|
Title Alternative | Multiple effects of statins in patients with bacterial infectious diseases
|
Author |
Nishitani, Noriko
Graduate School of Pharmaceutical Sciences, the University of Tokushima|Faculty of Pharmaceutical Sciences, Hiroshima International University
Fushitani, Syuji
Division of Pharmacy, Tokushima University Hospital
Shibata, Hirofumi
Department of Molecular Cell Biology and Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
KAKEN Search Researchers
Takiguchi, Masufumi
Faculty of Pharmaceutical Sciences, Hiroshima International University
Kawazoe, Kazuyoshi
Division of Pharmacy, Tokushima University Hospital|Department of Clinical Pharmacy, Institute of Health Biosciences, the University of Tokushima Graduate School
KAKEN Search Researchers
Yoshihara, Shin’ichi
Faculty of Pharmaceutical Sciences, Hiroshima International University
Minakuchi, Kazuo
Division of Pharmacy, Tokushima University Hospital|Department of Clinical Pharmacy, Institute of Health Biosciences, the University of Tokushima Graduate School
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
|
Keywords | statin
multiple effect
bacterial infection
sepsis
|
Content Type |
Journal Article
|
Description | Statins, treatments for dyslipidemia, have been reported to possess effects leading to the repair of the vascular endothelium, as well as anti-oxidative and anti-inflammatory effects, and their clinical usefulness has been focused on. It was also reported in previous clinical research that bacteremia patients on statins showed a lower mortality compared to those not receiving statins, and atherosclerosis patients on statins showed a significantly lower rate of severe or fatal sepsis compared to those not receiving them. We conducted a case-control study involving patients hospitalized in Tokushima University Hospital to evaluate the relationship between taking/not taking statins and bacterial infectious diseases. As a result, there was no relationship between taking/not taking statins and the overall patients with bacterial infectious diseases, but sepsis patients on statins showed a significantly lower mortality. The taking of statins was suggested to be useful for patients with bacterial infectious diseases, particularly males.
|
Journal Title |
四国医学雑誌
|
ISSN | 00373699
|
NCID | AN00102041
|
Publisher | 徳島医学会
|
Volume | 68
|
Issue | 1-2
|
Start Page | 29
|
End Page | 34
|
Sort Key | 29
|
Published Date | 2012-04-25
|
Remark | |
EDB ID | |
FullText File | |
language |
jpn
|
departments |
Pharmaceutical Sciences
Medical Sciences
|