ID | 97534 |
タイトルヨミ | サイキン カンセンショウ カンジャ ニオケル スタチン ノ タメンテキ コウカ
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タイトル別表記 | Multiple effects of statins in patients with bacterial infectious diseases
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著者 |
西谷, 典子
徳島大学大学院薬科学教育部|広島国際大学薬学部
伏谷, 秀治
徳島大学病院薬剤部
瀧口, 益史
広島国際大学薬学部
吉原, 新一
広島国際大学薬学部
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キーワード | statin
multiple effect
bacterial infection
sepsis
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資料タイプ |
学術雑誌論文
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抄録 | Statins, treatments for dyslipidemia, have been reported to possess effects leading to the repair of the vascular endothelium, as well as anti-oxidative and anti-inflammatory effects, and their clinical usefulness has been focused on. It was also reported in previous clinical research that bacteremia patients on statins showed a lower mortality compared to those not receiving statins, and atherosclerosis patients on statins showed a significantly lower rate of severe or fatal sepsis compared to those not receiving them. We conducted a case-control study involving patients hospitalized in Tokushima University Hospital to evaluate the relationship between taking/not taking statins and bacterial infectious diseases. As a result, there was no relationship between taking/not taking statins and the overall patients with bacterial infectious diseases, but sepsis patients on statins showed a significantly lower mortality. The taking of statins was suggested to be useful for patients with bacterial infectious diseases, particularly males.
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掲載誌名 |
四国医学雑誌
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ISSN | 00373699
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cat書誌ID | AN00102041
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出版者 | 徳島医学会
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巻 | 68
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号 | 1-2
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開始ページ | 29
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終了ページ | 34
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並び順 | 29
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発行日 | 2012-04-25
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備考 | |
EDB ID | |
フルテキストファイル | |
言語 |
jpn
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部局 |
薬学系
医学系
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