Bando, Hiroshi Tokushima University|Japan Low Carbohydrate Diet Promotion Association KAKEN Search Researchers
Kato, Yoshikane Kanaiso Hospital
Kanazawa, Setsuko Kanaiso Hospital
Tanaka, Mayumi Kanaiso Hospital
Sueki, Etsuko Kanaiso Hospital
Kanagawa, Hiroe Kanaiso Hospital
Kawata, Takafumi Kanaiso Hospital
Kawahito, Atsuko Kanaiso Hospital
Aihara, Aya Kanaiso Hospital
Continuous Glucose Monitoring (CGM)
Free Style Libre
type 1 diabetes mellitus (T1DM)
mean absolute relative difference (MARD)
low carbohydrate diet (LCD)
Japan LCD promotion association (JLCDPA)
Background: The problem of glucose variability has been in focus for type 1 diabetes mellitus (T1DM) on insulin treatment. Daily profile of blood glucose was studied on Continuous Glucose Monitoring (CGM) using Free Style Libre.
Case presentation and results: Patient is 54 year-old T1DM female, with HbA1c 7.8%. The blood glucose variability was measured by Free Style Libre. Insulin therapy included multiple daily insulin injection (MDI) of Insulin Glargin and Aspart. The result revealed unstable blood glucose profile in day 1 and 2. After that, the level and fluctuation of blood glucose gradually decreased from day 3 to 14. Average blood glucose in a day was 174mg/dL, 159mg/dL, 138mg/dL, 125mg/dL and 110mg/dL, in day 2, 4, 7, 9, 11, respectively. There was a discrepancy of HbA1c between 7.8% by laboratory measurement and 6.3% presumed value by Free Style Libre.
Discussion and Conclusion: Free Style Libre showed satisfactory results as CGM. There was lower HbA1c value by presumed calculation, which would be possibly due to every 15minutes measurement and difficulty in checking abrupt glucose surges. CGM application would probably bring diabetic subjects behavioral change of life style, leading to better diabetic control. These results would become reference data in CGM study for future research.
Journal of Diabetes, Metabolic Disorders & Control
©2019 Bando et al. This is an open access article distributed under the terms of the Creative Commons Attribution License(https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and build upon your work non-commercially.
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