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ID 119178
Author
Bando, Hiroshi Tokushima University|Medical research|Kanaiso Hospital KAKEN Search Researchers
Yamashita, Hisako Kanaiso Hospital
Kato, Yoshinobu Kanaiso Hospital
Ogura, Katsunori Kanaiso Hospital
Kato, Yoshikane Kanaiso Hospital
Keywords
Vildagliptin / Metformin (Equmet)
Imeglimin (Twymeeg)
Gastro-Intestinal Adverse Effects
Trials of Imeglimin for Efficacy and Safety
Vildagliptin Efficacy in Combination with Metformin for Early Treatment of Type 2 Diabetes
Content Type
Journal Article
Description
Background: Vildagliptin/Metformin (EquMet) and imeglimin (Twymeeg) are effective oral hypoglycemic agents (OHAs) for patients with type 2 diabetes (T2D).
Case Presentation: The patient was a 68-year-old male with T2D and fatty liver for several years. In November 2022, his HbA1c had increased to 8.2%, and he was started on Twymeeg, followed by EquMet.
Results: Over the course of four months, the patient’s HbA1c value successfully decreased from 8.2% to 6.7%, and he did not experience any gastrointestinal adverse effects (GIAEs).
Discussion and Conclusion: The combined treatment of EquMet and Twymeeg demonstrated clinical efficacy without any adverse effects. The Trials of IMeglimin for Efficacy and Safety (TIMES) provided various evidence of imeglimin’s effectiveness.
Journal Title
Asploro Journal of Biomedical and Clinical Case Reports
ISSN
25820370
Publisher
Asploro
Volume
6
Issue
2
Start Page
69
End Page
75
Published Date
2023-04-14
Rights
This is an open-access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
DOI (Published Version)
URL ( Publisher's Version )
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language
eng
TextVersion
Publisher
departments
Medical Sciences