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Pharmaceutical Sciences Shigenaga, Akira

Published Date (desc)
Tailored Synthesis of 162-Residue S-Monoglycosylated GM2-Activator Protein (GM2AP) Analogues that Allows Facile Access to Protein Library
Author Nakamura, Takahiro/ Sato, Kohei/ Naruse, Naoto/ Kitakaze, Keisuke/ Inokuma, Tsubasa/ Hirokawa, Takatsugu/ Shigenaga, Akira/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemBioChem
Volume 17
Issue 20
Published Date 2016-08-19
departments Pharmaceutical Sciences
Development of an Anilide-Type Scaffold for the Thioester Precursor N-Sulfanylethylcoumarinyl Amide
Author Eto, Mitsuhiro/ Naruse, Naoto/ Morimoto, Kyohei/ Yamaoka, Kosuke/ Sato, Kohei/ Tsuji, Kohei/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 18
Issue 17
Published Date 2016-08-16
departments Pharmaceutical Sciences
Labelling of Endogenous Target Protein via N–S Acyl Transfer-Mediated Activation of N-Sulfanylethylanilide
Author Denda, Masaya/ Morisaki, Takuya/ Kohiki, Taiki/ Yamamoto, Jun/ Sato, Kohei/ Sagawa, Ikuko/ Inokuma, Tsubasa/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic & Biomolecular Chemistry
Volume 14
Issue 26
Published Date 2016-05-31
departments Technical Support Department Pharmaceutical Sciences
An N-sulfanylethylanilide-based traceable linker for enrichment and selective labelling of target proteins
Author Morisaki, Takuya/ Denda, Masaya/ Yamamoto, Jun/ Tsuji, Daisuke/ Inokuma, Tsubasa/ Itoh, Kohji/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Communications
Volume 52
Issue 42
Published Date 2016-04-26
departments Pharmaceutical Sciences
Facile Preparation of Peptides with C-Terminal N-Alkylamide via Radical-Initiated Dethiocarboxylation
Author Shimizu, Tatsuhiko/ Miyajima, Rin/ Naruse, Naoto/ Yamaoka, Kosuke/ Aihara, Keisuke/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical and Pharmaceutical Bulletin
Volume 64
Issue 4
Published Date 2016-04-01
departments Pharmaceutical Sciences
Facile synthesis of C-terminal peptide thioacids under mild conditions from N-sulfanylethylanilide peptides
Author Shimizu, Tatsuhiko/ Miyajima, Rin/ Sato, Kohei/ Sakamoto, Ken/ Naruse, Naoto/ Kita, Miku/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 72
Issue 7
Published Date 2015-12-29
departments Pharmaceutical Sciences
Development of an intein-inspired amide cleavage chemical device
Author Komiya, Chiaki/ Aihara, Keisuke/ Morishita, Ko/ Ding, Hao/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title The Journal of Organic Chemistry
Volume 81
Issue 2
Published Date 2015-12-08
departments Pharmaceutical Sciences
Preparation of Peptide Thioesters from Naturally Occurring Sequences Using Reaction Sequence Consisting of Regioselective S-Cyanylation and Hydrazinolysis
Author Miyajima, Rin/ Tsuda, Yusuke/ Inokuma, Tsubasa/ Shigenaga, Akira/ Imanishi, Miki/ Futaki, Shiroh/ Otaka, Akira/
Content Type Journal Article
Journal Title Biopolymers(Peptide Science)
Volume 106
Issue 4
Published Date 2015-10-26
departments Pharmaceutical Sciences
Design and synthesis of a hydrogen peroxide-responsive amino acid that induces peptide bond cleavage after exposure to hydrogen peroxide
Author Kita, Miku/ Yamamoto, Jun/ Morisaki, Takuya/ Komiya, Chiaki/ Inokuma, Tsubasa/ Miyamoto, Licht/ Tsuchiya, Koichiro/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron Letters
Volume 56
Issue 28
Published Date 2015-05-21
departments Pharmaceutical Sciences
The total chemical synthesis of the monoglycosylated GM2 ganglioside activator using a novel cysteine surrogate
Author Sato, Kohei/ Kitakaze, Keisuke/ Nakamura, Takahiro/ Naruse, Naoto/ Aihara, Keisuke/ Shigenaga, Akira/ Inokuma, Tsubasa/ Tsuji, Daisuke/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Communications
Volume 51
Issue 49
Published Date 2015-05-13
departments Pharmaceutical Sciences
Synthesis of lactam-bridged cyclic peptides using sequential olefin metathesis and diimide reduction reactions
Author Aihara, Keisuke/ Inokuma, Tsubasa/ Komiya, Chiaki/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 71
Issue 24
Published Date 2015-05-01
departments Pharmaceutical Sciences
Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System
Author Tsuda, Yusuke/ Shigenaga, Akira/ Tsuji, Kohei/ Denda, Masaya/ Sato, Kohei/ Kitakaze, Keisuke/ Nakamura, Takahiro/ Inokuma, Tsubasa/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemistryOpen
Volume 4
Issue 4
Published Date 2015-04-28
departments Pharmaceutical Sciences
Liquid-Phase Synthesis of Bridged Peptides Using Olefin Metathesis of a Protected Peptide with a Long Aliphatic Chain Anchor
Author Aihara, Keisuke/ Komiya, Chiaki/ Shigenaga, Akira/ Inokuma, Tsubasa/ Takahashi, Daisuke/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 17
Issue 3
Published Date 2015-01-28
departments Pharmaceutical Sciences
刺激応答型アミノ酸の開発と生命科学分野への展開
Author Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Industry
Volume 65
Issue 11
Published Date 2014-11
departments Pharmaceutical Sciences
Development of a fluoride-responsive amide bond cleavage device that is potentially applicable to a traceable linker
Author Yamamoto, Jun/ Maeda, Nami/ Komiya, Chiaki/ Tanaka, Tomohiro/ Denda, Masaya/ Ebisuno, Koji/ Nomura, Wataru/ Tamamura, Hirokazu/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 70
Issue 34
Published Date 2014-06-06
departments Pharmaceutical Sciences
Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins
Author Yamamoto, Jun/ Denda, Masaya/ Maeda, Nami/ Kita, Miku/ Komiya, Chiaki/ Tanaka, Tomohiro/ Nomura, Wataru/ Tamamura, Hirokazu/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic & Biomolecular Chemistry
Volume 12
Issue 23
Published Date 2014-04-17
departments Pharmaceutical Sciences
Development of caged non-hydrolyzable phosphoamino acids and application to photo-control of binding affinity of phosphopeptide mimetic to phosphopeptide-recognizing protein
Author Ebisuno, Koji/ Denda, Masaya/ Ogura, Keiji/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Bioorganic & Medicinal Chemistry
Volume 22
Issue 11
Published Date 2014-04-13
departments Pharmaceutical Sciences
Development of a Reduction‐Responsive Amino Acid that Induces Peptide Bond Cleavage in Hypoxic Cells
Author Shigenaga, Akira/ Ogura, Keiji/ Hirakawa, Hiroko/ Yamamoto, Jun/ Ebisuno, Koji/ Miyamoto, Licht/ Ishizawa, Keisuke/ Tsuchiya, Koichiro/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemBioChem
Volume 13
Issue 7
Published Date 2012-04-13
departments Pharmaceutical Sciences Medical Sciences
刺激応答型アミノ酸の開発とケミカルバイオロジー分野への展開
Author Shigenaga, Akira/
Content Type Journal Article
Journal Title Journal of the Pharmaceutical Society of Japan
Volume 132
Issue 9
Published Date 2012
departments Pharmaceutical Sciences
Development of UV-responsive catch-and-release system of a cysteine protease model peptide
Author Shigenaga, Akira/ Morishita, Ko/ Yamaguchi, Keiko/ Ding, Hao/ Ebisuno, Koji/ Sato, Kohei/ Yamamoto, Jun/ Akaji, Kenichi/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 67
Issue 46
Published Date 2011-09-21
departments Pharmaceutical Sciences
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