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University Hospital Matsumoto, Toshio

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Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis
Author Dong, Bingzi/ Hiasa, Masahiro/ Higa, Yoshiki/ Ohnishi, Yukiyo/ Endo, Itsuro/ Kondo, Takeshi/ Takashi, Yuichi/ Tsoumpra, Maria/ Kainuma, Risa/ Sawatsubashi, Shun/ Kiyonari, Hiroshi/ Shioi, Go/ Sakaue, Hiroshi/ Nakashima, Tomoki/ Kato, Shigeaki/ Abe, Masahiro/ Fukumoto, Seiji/ Matsumoto, Toshio/
Content Type Journal Article
Journal Title Nature Communications
Volume 13
Published Date 2022-11-23
departments Oral Sciences Medical Sciences University Hospital Institute of Advanced Medical Sciences
Mechanical unloading aggravates bone destruction and tumor expansion in myeloma
Author Tanimoto, Kotaro/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Oda, Asuka/ Harada, Takeshi/ Higa, Yoshiki/ Sogabe, Kimiko/ Oura, Masahiro/ Sumitani, Ryohei/ Hara, Tomoyo/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Haematologica
Volume 107
Issue 3
Published Date 2021-11-18
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2
Author Higa, Yoshiki/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Nakaue, Emiko/ Tanaka, Mariko/ Kim, Sooha/ Nakagawa, Motosumi/ Shimizu, So/ Tanimoto, Kotaro/ Teramachi, Jumpei/ Harada, Takeshi/ Oda, Asuka/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Antioxidants
Volume 12
Issue 1
Published Date 2023-01-05
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Aberrant upregulation of the endogenous PP2A inhibitor CIP2A is vital for myeloma cell growth and survival
Author Shimizu, So/ Teramachi, Jumpei/ Harada, Takeshi/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Oda, Asuka/ Seki, Aiko/ Inoue, Yusuke/ Tanimoto, Kotaro/ Higa, Yoshiki/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Sawa, Yoshihiko/ Endo, Itsuro/ Tsuneyama, Koichi/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Myeloma
Volume 12
Issue 2
Published Date 2022
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Vascular Endothelial Function Is Associated with eGFR Slope in Female and Non-Smoking Male Individuals with Cardiovascular Risk Factors : A Pilot Study on the Predictive Value of FMD for Renal Prognosis
Author Masuda, Shiho/ Hara, Tomoyo/ Yamagami, Hiroki/ Mitsui, Yukari/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Harada, Takeshi/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Nakamura, Shingen/ Kuroda, Akio/ Endo, Itsuro/ Matsumoto, Toshio/ Matsuhisa, Munehide/ Abe, Masahiro/ Aihara, Ken-ichi/
Content Type Thesis or Dissertation
Journal Title Journal of Atherosclerosis and Thrombosis
Volume 30
Issue 11
Published Date 2023
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus
Author Hara, Tomoyo/ Uemoto, Ryoko/ Sekine, Akiko/ Mitsui, Yukari/ Masuda, Shiho/ Yamagami, Hiroki/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Kuroda, Akio/ Ikeda, Yasumasa/ Endo, Itsuro/ Honda, Soichi/ Yoshimoto, Katsuhiko/ Kondo, Akira/ Tamaki, Toshiaki/ Matsumoto, Toshio/ Matsuhisa, Munehide/ Abe, Masahiro/ Aihara, Ken-ichi/
Content Type Thesis or Dissertation
Journal Title Journal of Atherosclerosis and Thrombosis
Volume 30
Issue 8
Published Date 2023-08-01
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences Oral Sciences
Human Pituitary Adenomas Infrequently Contain Inactivation of Retinoblastoma 1 Gene and Activation of Cyclin Dependent Kinase 4 Gene
Author Honda, Soichi/ Tanaka-Kosugi, Chisato/ Yamada, Shozo/ Sano, Toshiaki/ Matsumoto, Toshio/ Itakura, Mitsuo/ Yoshimoto, Katsuhiko/
Content Type Journal Article
Journal Title Endocrine Journal
Volume 50
Issue 3
Published Date 2003
departments University Hospital Medical Sciences Institute of Advanced Medical Sciences Oral Sciences
Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma
Author Teramachi, Jumpei/ Hiasa, Masahiro/ Oda, Asuka/ Harada, Takeshi/ Nakamura, Shingen/ Amachi, Ryota/ Tenshin, Hirofumi/ Iwasa, Masami/ Fujii, Shiroh/ Kagawa, Kumiko/ Miki, Hirokazu/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Endo, Itsuro/ Haneji, Tatsuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Journal Article
Journal Title British Journal of Haematology
Volume 180
Issue 4
Published Date 2016-10-17
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
A vicious cycle between acid sensing and survival signaling in myeloma cells : acid-induced epigenetic alteration
Author Amachi, Ryota/ Hiasa, Masahiro/ Teramachi, Jumpei/ Harada, Takeshi/ Oda, Asuka/ Nakamura, Shingen/ Hanson, Derek/ Watanabe, Keiichiro/ Fujii, Shiro/ Miki, Hirokazu/ Kagawa, Kumiko/ Iwasa, Masami/ Endo, Itsuro/ Kondo, Takeshi/ Yoshida, Sumiko/ Aihara, Ken-Ichi/ Kurahashi, Kiyoe/ Kuroda, Yoshiaki/ Horikawa, Hideaki/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Journal Article
Journal Title Oncotarget
Volume 7
Issue 43
Published Date 2016-09-10
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
The Role of Heparin Cofactor II in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice
Author Kurahashi, Kiyoe/ Inoue, Seika/ Yoshida, Sumiko/ Ikeda, Yasumasa/ Morimoto, Kana/ Uemoto, Ryoko/ Ishikawa, Kazue/ Kondo, Takeshi/ Yuasa, Tomoyuki/ Endo, Itsuro/ Miyake, Masato/ Oyadomari, Seiichi/ Matsumoto, Toshio/ Abe, Masahiro/ Sakaue, Hiroshi/ Aihara, Ken-ichi/
Content Type Thesis or Dissertation
Journal Title Journal of Atherosclerosis and Thrombosis
Volume 24
Issue 12
Published Date 2017-12-01
departments University Hospital Medical Sciences Institute of Advanced Medical Sciences
Serum carboxy-terminal telopeptide of type I collagen levels are associated with carotid atherosclerosis in patients with cardiovascular risk factors
Author Kondo, Takeshi/ Endo, Itsuro/ Aihara, Ken-ichi/ Onishi, Yukiyo/ Dong, Bingzi/ Ohguro, Yukari/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Fujinaka, Yuichi/ Kuroda, Akio/ Matsuhisa, Munehide/ Fukumoto, Seiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Endocrine Journal
Volume 63
Issue 4
Published Date 2016-04-25
departments University Hospital Medical Sciences Institute of Advanced Medical Sciences
Serum carboxy-terminal telopeptide of type Ⅰ collagen (ICTP) as a surrogate marker for vulnerable plaques in atherosclerotic patients : a pilot study
Author Kato, Shuji/ Endo, Itsuro/ Fujimura, Mitsunori/ Kuriwaka-Kido, Rika/ Fujinaka, Yuichi/ Aihara, Ken-ichi/ Iwase, Takashi/ Inoue, Daisuke/ Akaike, Masashi/ Abe, Masahiro/ Matsumoto, Toshio/
Content Type Thesis or Dissertation
Journal Title Atherosclerosis
Volume 229
Issue 1
Published Date 2013-04-06
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors
Author Harada, Takeshi/ Ozaki, Shuji/ Oda, Asuka/ Tsuji, Daisuke/ Ikegame, Akishige/ Iwasa, Masami/ Udaka, Kengo/ Fujii, Shiro/ Nakamura, Shingen/ Miki, Hirokazu/ Kagawa, Kumiko/ Kuroda, Yoshiaki/ Kawai, Shigeto/ Itoh, Kohji/ Yamada-Okabe, Hisafumi/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title PLOS ONE
Volume 8
Issue 12
Published Date 2013-12-26
departments University Hospital Pharmaceutical Sciences Medical Sciences Institute of Advanced Medical Sciences
TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects
Author Tenshin, Hirofumi/ Teramachi, Jumpei/ Oda, Asuka/ Amachi, Ryota/ Hiasa, Masahiro/ Bat-Erdene, Ariunzaya/ Watanabe, Keiichiro/ Iwasa, Masami/ Harada, Takeshi/ Fujii, Shiroh/ Kagawa, Kumiko/ Sogabe, Kimiko/ Nakamura, Shingen/ Miki, Hirokazu/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Aihara, Kenichi/ Endo, Itsuro/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Blood Advances
Volume 1
Issue 24
Published Date 2017-10-26
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Diabetic Conditions Differentially Affect the Endothelial Function, Arterial Stiffness and Carotid Atherosclerosis
Author Kinouchi, Mizuho/ Aihara, Ken-ichi/ Fujinaka, Yuichi/ Yoshida, Sumiko/ Oogura, Yukari/ Kurahashi, Kiyoe/ Kondo, Takeshi/ Aki, Nanako/ Kuroda, Akio/ Endo, Itsuro/ Matsuhisa, Munehide/ Matsumoto, Toshio/
Content Type Thesis or Dissertation
Journal Title Journal of Atherosclerosis and Thrombosis
Volume 21
Issue 5
Published Date 2014-05-27
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
Activating transcription factor 4, an ER stress mediator , is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib
Author Nakamura, Shingen/ Miki, Hirokazu/ Kido, Shinsuke/ Nakano, Ayako/ Hiasa, Masahiro/ Oda, Asuka/ Amou, Hiroe/ Watanabe, Keiichiro/ Harada, Takeshi/ Fujii, Shiro/ Takeuchi, Kyoko/ Kagawa, Kumiko/ Ozaki, Shuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Hematology
Volume 98
Issue 1
Published Date 2013-05-25
departments Medical Sciences University Hospital Oral Sciences Institute of Advanced Medical Sciences
Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation
Author Hanson, Derek James/ Nakamura, Shingen/ Amachi, Ryota/ Hiasa, Masahiro/ Oda, Asuka/ Tsuji, Daisuke/ Itoh, Kohji/ Harada, Takeshi/ Horikawa, Kazuki/ Teramachi, Jumpei/ Miki, Hirokazu/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Oncotarget
Volume 6
Issue 32
Published Date 2015-09-10
departments Medical Sciences Oral Sciences Pharmaceutical Sciences University Hospital Institute of Advanced Medical Sciences
Calcilytic ameliorates abnormalities of mutant calcium-sensing receptor (CaSR) knock-in mice mimicking autosomal dominant hypocalcemia (ADH)
Author Dong, Bingzi/ Endo, Itsuro/ Ohnishi, Yukiyo/ Kondo, Takeshi/ Hasegawa, Tomoka/ Amizuka, Norio/ Kiyonari, Hiroshi/ Shioi, Go/ Abe, Masahiro/ Fukumoto, Seiji/ Matsumoto, Toshio/
Content Type Thesis or Dissertation
Journal Title Journal of Bone and Mineral Research
Volume 30
Issue 11
Published Date 2015-05-12
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells
Author Asano, Jin/ Nakano, Ayako/ Oda, Asuka/ Amou, Hiroe/ Hiasa, Masahiro/ Takeuchi, Kyoko/ Miki, Hirokazu/ Nakamura, Shingen/ Harada, Takeshi/ Fujii, Shiro/ Kagawa, Kumiko/ Endo, Itsuro/ Yata, Kenichiro/ Sakai, Akira/ Ozaki, Shuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Leukemia
Volume 25
Issue 7
Published Date 2011-04-08
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis : Suppressive Effects of Febuxostat
Author Ashtar, Mohannad/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Bat-Erdene, Ariunzaya/ Hiasa, Masahiro/ Oda, Asuka/ Tanimoto, Kotaro/ Shimizu, So/ Higa, Yoshiki/ Harada, Takeshi/ Oura, Masahiro/ Sogabe, Kimiko/ Nakamura, Shingen/ Fujii, Shiro/ Sumitani, Ryohei/ Miki, Hirokazu/ Udaka, Kengo/ Takahashi, Mamiko/ Kagawa, Kumiko/ Endo, Itsuro/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Cancers
Volume 12
Issue 4
Published Date 2020-04-09
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
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