ID | 110654 |
Author |
Satake, Nobuo
Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine
Uehara, Hisanori
Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Sano, Nobuya
Division of Surgical Pathology, University Hospital, The University of Tokushima School of Medicine
Kubo, Takayuki
Division of Surgical Pathology, University Hospital, The University of Tokushima School of Medicine
Sasa, Mitsunori
Tokushima Breast Care Clinic
Izumi, Keisuke
Department of Molecular and Environmental Pathology, The University of Tokushima School of Medicine
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
|
Keywords | breast
fine-needle aspiration biopsy cytology
glycogen-rich carcinoma
c-erbB-2
cytology
|
Content Type |
Journal Article
|
Description | Background : Glycogen-rich carcinoma is a rare special histologic subtype of breast cancer and its incidence is estimated to be 1.4% in breast malignancies. However, its precise characteristics in cytological specimens have not yet been fully clarified. Case : Fifty-nine-year-old and 53-year-old women underwent fine-needle aspiration biopsy cytology (FNABC) of a breast tumor, confirming malignancy. A mastectomy with axillary dissection was performed. Cytologically, a moderate amount of eosinophilic, finely granular cytoplasm was seen in the majority of the tumor cells, however, foamy and vacuolated cytoplasm was noted in some tumor cells. Histologically, the tumor cells of both cases had clear and granular cytoplasm, which showed a positive reaction with periodic acid-Schiff, eliminated by diastase. Conclusion : While clear cytoplasm in the tumor cells in the FNABC seemed to be a pivotal cytological characteristic of glycogen-rich carcinoma, it may not be a major component of cytological specimens. Routine periodic acid-Schiff staining may be required to diagnose glycogen-rich carcinoma in cytological methods.
|
Journal Title |
The journal of medical investigation : JMI
|
ISSN | 13431420
|
NCID | AA11166929
|
Volume | 49
|
Issue | 3-4
|
Start Page | 193
|
End Page | 196
|
Sort Key | 193
|
Published Date | 2002
|
EDB ID | |
FullText File | |
language |
eng
|
TextVersion |
Publisher
|
departments |
University Hospital
Medical Sciences
|