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ID 115492
Title Alternative
Enantiomer-selective Anti-influenza Activity of Bakuchiol
Author
Shoji, Masaki Tokushima Bunri University
Arakaki, Yumie Tokushima Bunri University
Esumi, Tomoyuki Tokushima Bunri University
Kohnomi, Shuntaro Tokushima Bunri University
Yamamoto, Chihiro Tokushima Bunri University
Suzuki, Yutaka University of Tokyo
Konishi, Shiro Tokushima Bunri University
Kuzuhara, Takashi Tokushima Bunri University
Content Type
Journal Article
Description
Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds.
Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway.
Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity.
Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy.
Journal Title
Journal of Biological Chemistry
ISSN
00219258
NCID
AA1202441X
Publisher
The American Society for Biochemistry and Molecular Biology
Volume
290
Issue
46
Start Page
28001
End Page
28017
Published Date
2015-10-07
Rights
Final version free via Creative Commons CC-BY license(https://creativecommons.org/licenses/by/4.0/).
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Institute of Advanced Medical Sciences