| ID | 115492 |
| Title Alternative | Enantiomer-selective Anti-influenza Activity of Bakuchiol
|
| Author |
Shoji, Masaki
Tokushima Bunri University
Arakaki, Yumie
Tokushima Bunri University
Esumi, Tomoyuki
Tokushima Bunri University
Kohnomi, Shuntaro
Tokushima Bunri University
Yamamoto, Chihiro
Tokushima Bunri University
Suzuki, Yutaka
University of Tokyo
Takahashi, Etsuhisa
Tokushima University
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Konishi, Shiro
Tokushima Bunri University
Kido, Hiroshi
Tokushima University
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Kuzuhara, Takashi
Tokushima Bunri University
|
| Content Type |
Journal Article
|
| Description | Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds.
Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway. Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity. Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy. |
| Journal Title |
Journal of Biological Chemistry
|
| ISSN | 00219258
|
| NCID | AA1202441X
|
| Publisher | The American Society for Biochemistry and Molecular Biology
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| Volume | 290
|
| Issue | 46
|
| Start Page | 28001
|
| End Page | 28017
|
| Published Date | 2015-10-07
|
| Rights | Final version free via Creative Commons CC-BY license(https://creativecommons.org/licenses/by/4.0/).
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| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
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| TextVersion |
Publisher
|
| departments |
Institute of Advanced Medical Sciences
|
