ID | 115492 |
タイトル別表記 | Enantiomer-selective Anti-influenza Activity of Bakuchiol
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著者 |
Shoji, Masaki
Tokushima Bunri University
Arakaki, Yumie
Tokushima Bunri University
Esumi, Tomoyuki
Tokushima Bunri University
Kohnomi, Shuntaro
Tokushima Bunri University
Yamamoto, Chihiro
Tokushima Bunri University
Suzuki, Yutaka
University of Tokyo
Konishi, Shiro
Tokushima Bunri University
Kuzuhara, Takashi
Tokushima Bunri University
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資料タイプ |
学術雑誌論文
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抄録 | Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds.
Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway. Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity. Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy. |
掲載誌名 |
Journal of Biological Chemistry
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ISSN | 00219258
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cat書誌ID | AA1202441X
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出版者 | The American Society for Biochemistry and Molecular Biology
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巻 | 290
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号 | 46
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開始ページ | 28001
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終了ページ | 28017
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発行日 | 2015-10-07
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権利情報 | Final version free via Creative Commons CC-BY license(https://creativecommons.org/licenses/by/4.0/).
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言語 |
eng
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著者版フラグ |
出版社版
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部局 |
先端酵素学研究所
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