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ID 111901
Author
Shigenaga, Akira The University of Tokushima KAKEN Search Researchers
Yamamoto, Jun The University of Tokushima
Hirakawa, Hiroko The University of Tokushima
Ogura, Keiji The University of Tokushima
Maeda, Nami The University of Tokushima
Morishita, Ko The University of Tokushima
Content Type
Journal Article
Description
To develop a thiol-responsive DNA releasing system, a thiol-responsive amino acid capable of inducing an amide bond cleavage in the presence of a thiol was developed. It was successfully combined with peptide nucleic acid (PNA), and thiol-induced release of DNA from the thiol-responsive PNA/DNA complex was observed.
Journal Title
Tetrahedron Letters
ISSN
00404039
NCID
AA00861801
AA11539822
Publisher
Elsevier Ltd.
Volume
51
Issue
18
Start Page
2525
End Page
2528
Published Date
2010-03-03
Rights
©2010. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Pharmaceutical Sciences