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ID 115971
Title Alternative
栄養サポート介入患者における低ナトリウム血症の要因 : 生体電気インピーダンス法による横断研究
Clinical Characteristics of Hyponatremia
Author
Yano, Mayumi Tokushima University
Inoue, Arisa Tokushima University
Toda, Akiyo Konan Women’s University
Takahashi, Michiko Kobe University
Usami, Makoto Konan Women’s University
Keywords
Hyponatremia
bioelectrical impedance analysis
fluid volume imbalance
the ratio of extracellular water to total body water
Content Type
Thesis or Dissertation
Description
Background & aims : We investigated the contributing factors of hyponatremia in patients on nutrition support using bioelectrical impedance analysis (BIA). Methods : Thirty patients administered enteral or parenteral nutrition support for at least 72 hours were studied. We collected nutritional and electrolyte intake, serum biochemical parameters, and body composition measured by BIA. Patients were classified into two groups according to their serum sodium levels : (1) Normanatremia group, 135–145 mEq / L (n = 18) and (2) Hyponatremia group, less than 135 mEq / L (n = 12), and their characteristics were analyzed. Results : There were no significant differences between the Normonatremia and Hyponatremia groups in terms of energy, protein, and sodium intake. Serum biochemical parameters other than serum sodium and chloride levels were comparable between the two groups. On the other hand, the ratio of extracellular water to total body water (ECW / TBW) obtained by BIA was significantly higher in the Hyponatremia group than in the Normonatremia group. Further, an elevated ECW / TBW significantly and negatively correlated with serum albumin level. Conclusions : Regardless of sodium intake, higher ECW / TBW was associated with hyponatremia in patients on nutrition support. ECW / TBW may be an important clinical parameter relevant to the nutritional care of hyponatremia.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
68
Issue
1-2
Start Page
112
End Page
118
Sort Key
112
Published Date
2021-02
Remark
内容要旨・審査要旨・論文本文の公開
本論文は,著者Mayumi Yanoの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3511号
Diploma Number
甲栄第285号
Granted Date
2021-03-23
Degree Name
Doctor of Nutritional Science
Grantor
Tokushima University
departments
Medical Sciences