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ID 116570
Title Alternative
Diagnostic utility of FeNO for CTVA
Author
Hanibuchi, Masaki Shikoku Central Hospital of the Mutual aid Association of Public School teachers Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kajimoto, Tatsuya Shikoku Central Hospital of the Mutual aid Association of Public School teachers
Saijo, Atsuro Shikoku Central Hospital of the Mutual aid Association of Public School teachers KAKEN Search Researchers
Kitagawa, Tetsuya Shikoku Central Hospital of the Mutual aid Association of Public School teachers Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
chest tightness variant asthma
fractional exhaled nitric oxide
biomarker
Content Type
Journal Article
Description
A 50-year-old woman was referred to our hospital for further examination of severe constricting pain at the right-side dominant anterior chest. She had medical history of outgrown childhood asthma and allergies to several animals. Chest auscultation revealed no wheezes, rhonchi and other crackles. Laboratory findings showed an eosinophilia and an elevation of total immunoglobulin E. The results of an electrocardiogram, a chest X-ray and a chest CT were unremarkable. A fractional exhaled nitric oxide value remarkably elevated, but the abnormalities in pulmonary function test were modest. Her chest pain was ameliorated after inhaling procaterol. Based on these findings, a diagnosis of chest tightness variant asthma was formulated, and we started treatment with inhaled corticosteroid / long acting β2 agonist. At two-weeks after treatment, her symptom markedly improved and a fractional exhaled nitric oxide value decreased, which led to a definitive diagnosis of chest tightness variant asthma. A fractional exhaled nitric oxide value further decreased to the normal range in consistent with symptom disappearance at 10-months after treatment, indicating the usefulness of fractional exhaled nitric oxide as a promising marker for the diagnosis and clinical improvement of chest tightness variant asthma.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
68
Issue
3-4
Start Page
389
End Page
392
Sort Key
389
Published Date
2021-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences